This prospective study assessed whether respiratory variations in velocity time integral, peak blood flow velocity and non-invasive pleth variability index are useful measurements in infants undergoing congenital heart surgery and determined threshold values that may help guide fluid administration. In 27 infants receiving mechanical ventilation, of mean (SD) weight 10.4 (6.3) kg, 13 increased ...

OBJECTIVE To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. DESIGN AND METHODS Sixty-two patients subject to elective open gastrointestinal surgery were evaluated during a peri...

UNLABELLED Background : Anti-CCP is a test commonly used for the diagnosis of rheumatoid arthritis. The aim of this study was to determine the diagnostic values of ACCP compared to anti-MCV in rheumatoid arthritis patients in north of Iran. METHODS The serum samples of 150 RA patients and 75 controls, with the mean age of 49.6+11.8 and 48.8+12 years respectively, were tested using the commerc...

BACKGROUND Diagnostic and prognostic or predictive models serve different purposes. Whereas diagnostic models are usually used for classification, prognostic models incorporate the dimension of time, adding a stochastic element. CONTENT The ROC curve is typically used to evaluate clinical utility for both diagnostic and prognostic models. This curve assesses how well a test or model discrimin...

Receiver operating characteristic (ROC) curve is widely applied in measuring discriminatory ability of diagnostic or prognostic tests. This makes the ROC analysis one of the most active research areas in medical statistics. Many parametric and semiparametric estimation methods have been proposed for estimating the ROC curve and its functionals. In this paper, we propose the Bayesian bootstrap (...

To verify the efficiency and to determine the cutoff values that discriminate children/adolescents with and without vocal complaints, as well as the measures of sensibility, specificity and efficiency of the Brazilian Pediatric Voice-Related Quality-of-Life Survey (P-VRQOL). The participants included 230 parents of children/adolescents of both genders, aged between 2 years and 18 years, with an...

The area under an ROC curve (AUC) has been advocated as an evaluation criterion for bipartite ranking problems. In this paper, we study large deviation properties of the AUC; in particular, we derive a distribution-free large deviation bound for the AUC which serves to bound the expected accuracy of a ranking function in terms of its empirical AUC on an independent test sequence.1 A comparison ...