OBJECTIVES The purpose of this study was to determine whether the number of bibliographic databases used to search the health sciences literature in individual systematic reviews (SRs) and meta-analyses (MAs) changed over a twenty-year period related to the official 1995 launch of the Cochrane Database of Systematic Reviews (CDSR). METHODS Ovid MEDLINE was searched using a modified version of...

The problem of searching a polygonal region for an unpredictably moving intruder by a set of stationary guards, each carrying an orientable laser, is known as the Searchlight Scheduling Problem. Determining the computational complexity of deciding if the polygon can be searched by a given set of guards is a long-standing open problem. Here we propose a generalization called the Partial Searchli...

Cleft palate (CP) is one of the most common congenital malformations. It can occur as part of a recognisable syndrome, associated with other malformations or, most commonly, be non-syndromic (CPO) (MIM 119540). The birth prevalence of CPO varies between and among populations but it is seen world wide. The highest incidence has been found in Finland, 1.01 per 1000 livebirths. Within Finland, the...