This paper gives a brief introduction to some of the experimental facilities at Caltech being used for instruction and research. Two experiments are described: a ight control experiment using a vector thrust engine, and a low-speed, axial ow compressor rig. A common hardware and software infrastructure is used to control these experiments, allowing easy transition from instructional to research...

Vitamin A can significantly decrease measles-associated morbidity and mortality. Vitamin A can inhibit the replication of measles virus (MeV) in vitro through an RARα- and type I interferon (IFN)-dependent mechanism. Retinoid-induced gene I (RIG-I) expression is induced by retinoids, activated by MeV RNA and is important for IFN signaling. We hypothesized that RIG-I is central to retinoid-media...

conclusions our results showed that only 17% of the measured points in the oil drilling rig floor were in safe area; 39% were in caution area and 44% were in danger area. in the camp facilities area, 51% of the points were in safe area, 38% were in caution area and 11% in danger area. the main sources of noise exposure in the rig floor area were power generators. materials and methods this was ...

Protein ubiquitination plays an essential role in the regulation of retinoic acid-inducible gene I (RIG-I) activation and the antiviral immune response. However, the function of the opposite process of deubiquitination in RIG-I activation remains elusive. In this study, we have identified the deubiquitinating enzyme ubiquitin-specific protease 4 (USP4) as a new regulator for RIG-I activation th...

in order to investigate the effect of water stress at heading stage on grain yield and yield components of eight wheat cultivars, in 2008 year a research was conducted in the two regions esfahan and ardestan by using split plot in a randomized complete block design with three replications which that two irrigation treatments included custom and late season water stress were main factor and 8 wh...

The caspase recruitment domain (CARD) of intracellular adaptors and sensors plays a critical role in the assembly of signaling complexes involved in innate host defense against pathogens and in the regulation of inflammatory responses. The cytosolic receptor retinoic acid-inducible gene-I (RIG-I) recognizes viral RNA in a 5'-triphosphate-dependent manner and initiates an antiviral signaling cas...

Exogenous nucleic acids induce an innate immune response in mammalian host cells through activation of the retinoic acid-inducible gene I (RIG-I). We evaluated RIG-I protein for RNA binding and ATPase stimulation with RNA ligands to investigate the correlation with the extent of immune response through RIG-I activation in cells. RIG-I protein favored blunt-ended, double-stranded RNA (dsRNA) lig...

Economic comparison of single-rig and twin-rig trawl for nephrops Economic comparison of single-rig and twin-rig trawl for nephrops

RIG-I senses intracellular virus-specific nucleic acid structures and initiates an antiviral response that induces interferon (IFN) production, which, in turn, activates the transcription of RIG-I to increase RIG-I protein levels. Upon intracellular poly(I:C) stimulation, however, the levels of RIG-I protein did not correlate with the expression patterns of RIG-I transcripts. When the ISG15 con...