Arboviruses are pathogens that widely affect the health of people in different communities around the world. Recently, a few successful approaches toward production of effective vaccines against some of these pathogens have been developed, but treatment and prevention of the resulting diseases remain a major health and research concern. The arbovirus infection and replication processes are comp...

Arthropod-borne viruses (arboviruses) pose a significant threat to global health, causing human disease with increasing geographic range and severity. The recent availability of the genome sequences of medically important mosquito species has kick-started investigations into the molecular basis of how mosquito vectors control arbovirus infection. Here, we discuss recent findings concerning the ...

Thirty-five strains of arbovirus were tested for replication in mouse embryo cell cultures; twenty-six of these multiplied and were cytopathogenic. Dengue I and dengue 2 may have multiplied without cytopathogenicity. Twenty-three of the viruses were also tested for the production of complement-fixing antigen; twentytwo were positive. Similar end-points were attained using standard inoculum dose...

Oropouche virus (arbovirus family Bunyaviridae, Simbu serological group) was experimentally transmitted from man to hamster by the bite of the midge Culicoides paraensis. Infection rates and transmission rates were determined after the midge had engorged on patients with viremia. The threshold titer necessary to enable infection or transmission by the midges was approximately 5.3 log10 of the m...

We isolated an arbovirus from bovine blood in Indonesia. The arbovirus was obtained from the plasma of a cow showing no clinical symptoms in West Java in February 2014, and was identified as Akabane virus (AKAV) by AKAV-specific RT-PCR and subsequent sequence analysis. Phylogenetic analysis based on partial S segment indicated the AKAV isolate, WJ-1SA/P/2014, was most closely related with two i...

Arthropod-borne virus encephalitis in the U.S.A. includes LaCrosse, St Louis, western equine, eastern equine, Venezuelan equine, and Powassan in that order of frequency. Diagnosis can be aided by the history of seasonal occurrence, climate, geographic location, exposure to vectors, and age of the patient. The definitive diagnosis is usually made by serological tests such as neutralization, comp...

1249 Arbovirus inhibition phenotype Arboviruses transmitted by mosquitoes have great importance in global health, owing to increasing ranges and impact and often with no effective vaccines or reliable prophylactics available. The most important is the flavivirus dengue virus (DENV), which occurs in 100 countries and causes tens of millions of cases of dengue fever annually, approximately half a...

During a 4-year period (1972-1975), mosquitoes were collected, identified, and processed for virus isolation. Laboratory examinations of clinical specimens from suspected encephalitis cases were made to provide etiologic diagnosis. Arbovirus was isolated from 102 pools of mosquitoes (2 LaCrosse, 2 Cache Valley, 10 Flanders, 3 St. Louis Considerable interest in arbovirus surveillance activity wa...