نتایج جستجو برای: aquaretic activity
تعداد نتایج: 1134390 فیلتر نتایج به سال:
Hyponatremia defined as a plasma sodium concentration of less than 135 mmol/L is a very common disorder, occurring in hospitalized patients. Hyponatremia often results from an increase in circulating arginine vasopressin (AVP) levels and/or increased renal sensitivity to AVP, combined with an increased intake of free water. Hyponatremia is subdivided into three groups, depending on clinical his...
چکیده : مقدمه : ابتلا به آترواسکلروز در بیماران دیابتی بیشتر از افراد سالم می باشد . هموسیستئین می تواند به عنوان یکی از عوامل خطرزای آترواسکلروز مطرح با شد . آنزیم لستین کلسترول آسیل ترنسفراز نقش مهمی را در پاک سازی کلسترول آزاد در بافت ها از طریق عملکرد hdl-c بر عهده دارد .هدف از این مطالعه تعیین سطح فعالیت لستین کلسترول آسیل ترنسفراز (lcat activity ) در بیماران دیابتی نوع 2 در مقایسه با افر...
IntroductionAutosomal dominant polycystic kidney disease (ADPKD) is the most prevalent genetic cause of failure. Tolvaptan, a vasopressin 2 receptor antagonist, first drug with proven disease-modifying activity. Long-term treatment adherence crucial, but considerable fraction patients discontinue treatment, because aquaretic side effects.MethodsTwenty-four-hour urine was collected in 75 ADPKD d...
Mutations in PKD1 are associated with autosomal dominant polycystic kidney disease. Studies in mouse models suggest that the vasopressin (AVP) V2 receptor (V2R) pathway is involved in renal cyst progression, but potential changes before cystogenesis are unknown. This study used a noncystic mouse model to investigate the effect of Pkd1 haploinsufficiency on water handling and AVP signaling in th...
Hyponatremia is the most common electrolyte disorder in hospitalized patients. Many studies documented that it was related to increased morbidity and mortality in patients with congestive heart failure, liver cirrhosis, and neurologic diseases. Although knowledge of hyponatremia has been cumulated, the optimal management of hyponatremia remains incompletely established in clinical practice beca...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید