نتایج جستجو برای: apolipoprotein c
تعداد نتایج: 1075318 فیلتر نتایج به سال:
Apolipoprotein C-III deficiency provides cardiovascular protection, but apolipoprotein C-III is not known to be associated with human amyloidosis. Here we report a form of amyloidosis characterized by renal insufficiency caused by a new apolipoprotein C-III variant, D25V. Despite their uremic state, the D25V-carriers exhibit low triglyceride (TG) and apolipoprotein C-III levels, and low very-lo...
A non-competitive sandwich enzyme-linked immunosorbent assay for apolipoprotein C-I was developed. Sheep antibody to this apolipoprotein C-I, purified by affinity chromatography, was used for coating the wells of a microtiter plate and as a conjugate with alkaline phosphatase. The linear range of the assay was from 80 ng to 15 ng. It was sensitive down to 5 ng. The intra-assay variation coeffic...
This study reports the changes in total cholesterol, triacylglycerols, apolipoproteins A-I, B, C-II and (a) before, directly after and 48 hours after chronic renal dialysis on 46 non-selected patients (20 male, 26 female; time since first dialysis 1-203 months (median 22 months), median age 52 years, range 25-82 years). Thirty six of the 46 patients (17 men and 19 women) suffered from hypertens...
Background: Type 2 diabetes mellitus (Type DM), characterized by a relative insulin deficiency or resistance, is associated with cluster of metabolic abnormalities, which includes glucose intolerance, hypertension, unique dyslipidemia, procoagulant state, and an increase in macrovascular diseases. Aims Objectives: The present study was conducted to correlate between fasting postprandial apolipo...
It is becoming increasingly accepted that removal of cellular cholesterol occurs by at least two pathways, one involving the well-described aqueous diffusion mechanism and another promoted by lipid-free apolipoproteins. We compared the contribution of apolipoprotein-dependent and -independent pathways, taking into consideration the influence of cellular metabolism, on cholesterol efflux promote...
We previously reported a family with apolipoprotein C-II (apoC-II) deficiency characterized by the presence of a mutant apoC-II, apoC-IIToronto. We now report the purification and primary structure of apoC-IIToronto. The sequence of apoC-IIToronto is identical to that of normal apoC-II from residues 1-68. It differs from residue 69, where Asp69-Gln70-Val71-Leu72-Ser73-Val74- Leu75-Lys76-Gly77-G...
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