UNLABELLED The aim of our study was to investigate the effects of atorvastatin on serum levels of total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), apolipoprotein A1 (apoA1), apolipoprotein B (apoB) and lipoprotein (a) in patients with primary hyperlipidemia and established coronary heart disease. MATERIAL AND METHODS A group of 96 patients (pts), of both ...

Aim: In this study we researched the effect of chronic hepatitis C virus (HCV) infection on serum lipid profile. Method: 28 patients (age average: 58.2±7.9 years) 17 of them women and 11 of them men and 33 healthy people (age average: 51.1±7.4 years) 22 of them women and 11 of them men taking chronic hepatitis C diagnosis through liver biopsy and in that any treatment wasn’t started yet were ta...

We report here results of a worldwide survey of apolipoprotein (apo) A1 and B measurements. A lyophilized pool of human serum was developed for the survey to test its suitability as a candidate Reference Material. Seventy-five laboratories from 18 countries responded to invitations to participate. Using several methods, they evaluated the mass concentration of apo A1 and B in the proposed Refer...

CA125 as a biomarker of ovarian cancer is ineffective for the general population. The aim of this study was to evaluate multiplexed bead-based immunoassay of multiple ovarian cancer-associated biomarkers such as transthyretin and apolipoprotein A1, together with CA125, to improve the identification and evaluation of prognosis of ovarian cancer. We measured the serum levels of CA125, transthyret...

AIMS To determine the burden of atherogenic apolipoprotein particles in early-onset type 2 diabetes (T2D) compared to those with later-onset disease during statin treatment. METHODS Early and later-onset T2D was defined as current age below and above 40 years respectively. Conventional lipid profile, LDL, non-HDL cholesterol, apolipoprotein B and A1 were determined in those without cardiovasc...

■ ■ Excellent linearity, accuracy, and precision INTRODUCTION Apolipoprotein A1 (Apo A1) protein is a major component of High Density Lipoprotein (HDL) in plasma. Along with other lipoproteins, Apo A1 plays a key role in lipid metabolism.1 While typical levels of Apo A1 are >1.2 mg/mL for males and >1.4 mg/mL for females,2 reduced plasma concentrations of Apo A1 have been reported in patients a...