Currently, there are no studies in the literature evaluating salivary fluoride retention after small amounts of fluoride gel are applied to children's teeth. Therefore, the objective of the present study was to compare salivary retention after gel application using a toothbrush or by traditional application with trays. In this crossover study, children with active caries (n = 10) were randomize...

In vivo enamel fluoride (F) uptake as a function of time after a single application of a new topical APF gel, MinuteGelTM (gel A) , was compared to a control APF gel, Nupro ® (gel B). The retained F in enamel after different post-treatment intervals also was assessed. Forty orthodontic patients aged 10-16 with four premolars scheduled for extraction were divided into two subgroups according to ...

Due to concerns about the potential for acute toxicity following professional application of topical fluoride, this clinical trial was undertaken to determine if half-strength acidulated phosphate fluoride (APF) would be as clinically effective in reducing caries as the currently used 1.23% APF. Three hundred and sixteen junior high school students, 11-15 years of age, living in a nonfluoridate...

A small heat-stable polypeptide, ATP-dependent proteolysis factor 1 (APF-1), is an essential component of the ATP-dependent proteolytic system of rabbit reticulocytes (Ciechanover, A., Hod, Y., and Hershko. A. (1978) Biochem. Biophys. Res Commun. 81, 1100-1105). The following evidence supports the view that APF-1 is ubiquitin, a highly conserved heat-stable polypeptide found universally in natu...

A randomized controlled parallel clinical trial was conducted to evaluate the efficacy of association 1.23% topical professional acidulated phosphate fluoride (APF) gel with oral hygiene and dietary instructions on arrest active non-cavitated lesions in permanent, mixed, temporary dentition children between 3 12 years age. Ninety-eight caries-active were randomly divided into two groups: a grou...

The purpose of this in vitro study was to determine the combined effects of argon laser irradiation (ArI) and acidulated phosphate fluoride treatment (APF) on caries-like lesion formation in human enamel. Each specimen was divided into tooth quarters with each quarter assigned to one of four groups: 1) control; 2) ArI Only; 3) ArI before APF treatment; 4) APF treatment before ArI. After a fluor...

OBJECTIVE This in situ/ex vivo study investigated the effect of CO2 laser irradiation and acidulated phosphate fluoride gel (APF) application, separately and in combination, on enamel resistance to erosion. MATERIAL AND METHODS During 2 experimental 5-day crossover phases, 8 volunteers wore intraoral appliances containing bovine enamel blocks which were submitted to four groups: 1st phase - c...

OBJECTIVE This study evaluated the surface degradation effect of acidulated phosphate fluoride (APF) gel exposure on the glassy matrix ceramics as a function of time. MATERIAL AND METHODS Disc-shaped ceramic specimens (N = 120, 10/per ceramic material) were prepared in stainless steel molds (inner diameter: 5 mm, height: 2 mm) using 6 dental ceramics: 3 indicated for ceramic-fused-to-metal (V...

AIM This study aims to estimate the cost-effectiveness from a societal perspective of seven dental caries prevention programmes among schoolchildren in Chile: three community-based programmes: water-fluoridation, salt-fluoridation and dental sealants; and four school-based programmes: milk-fluoridation; fluoridated mouthrinses (FMR); APF-Gel, and supervised toothbrushing with fluoride toothpast...