Background and Aims: Diabetes mellitus is accompanied with higher incidence of cardiovascular disorders. There is some evidence on antidiabetic potential of silymarin. In this study the effect of chronic administration of silymarin on contractile-relaxation response of thoracic aorta of diabetic rats was investigated. Methods: In this experimental study, male Wistar rats were divided into 5 gro...

Angiotensin II is a major endocrine hormone that affects directly both vascular smooth muscle and endothelial cells. Since vascular reactivity to angiotensin II changes in more physiological and pathophysiological conditions, the present study was performed to investigate the effect of intraperitoneal administration of angiotensin-converting enzyme inhibitor and captopril (30 and 50 mg kg-1, on...

Hypertension is one of the leading diseases cardiovascular system. It manifested by changes in arterial stiffness. Cardiovascular reactivity, especially blood pressure (BP), during cold pressor test (CPT) depending on various factors. Undoubtedly, stress most important The aim study to investigate effects CPT responses healthy young subjects. 56 individuals aged between 21 and 26 years have bee...

mycotic aortic aneurysms account for 1–3% of all aortic aneurysms. the management of this disease is controversial. since open surgical repair is associated with high morbidity and mortality rates, endovascular aneurysm repair is an alternative treatment method with promising early and midterm outcomes, although its long-term durability is unknown. secondary aortoenteric fistulas may occur iatr...

Abstract Background and Objective: Vascular abnormality and dysfunction plays an important role in the pathogenesis of vascular disease in diabetic state. In this study, we aimed to investigate whether an in vitro exposure of endothelium-intact aortic rings to Melissa officinalis (lemon balm, MO) aqueous extract could have a beneficial effect in rats with subchronic diabetes. Materials and Meth...

abstract background and objective: vascular abnormality and dysfunction plays an important role in the pathogenesis of vascular disease in diabetic state. in this study, we aimed to investigate whether an in vitro exposure of endothelium-intact aortic rings to melissa officinalis (lemon balm, mo) aqueous extract could have a beneficial effect in rats with subchronic diabetes. materials and meth...

angiotensin ii is a major endocrine hormone that affects directly both vascular smooth muscle and endothelial cells. since vascular reactivity to angiotensin ii changes in more physiological and pathophysiological conditions, the present study was performed to investigate the effect of intraperitoneal administration of angiotensin-converting enzyme inhibitor and captopril (30 and 50 mg kg-1, on...

Although classic and standard procedure for patients with ascending Aorta aneurysm with Sever aortic Regurgitation is Bentall surgery but in some selected cases this complex surgery was not performed with different reason like advanced age and coexisting comorbidity involving renal and hepatic and lung Function. In our cases 75 years old man with chronic renal failure ( Cr= 3.2 ) who was known ...

In rats, removal of the carotid arterial or abdominal aortic endothelium results in an acute increase of diameter and compliance. In humans, acute local administration of a specific NO synthase inhibitor increases radial artery compliance but not the diameter. The purpose of this review is to determine whether in spontaneously hypertensive rats (SHR), a cause-and-effect relationship may be obse...