A pilot project to assess the benefit of a psychology service in general practice for patients with anxiety is described. A course of lessons in ;anxiety management skills' was provided at two practices. At a follow-up appointment one year later two thirds of the 35 patients studied had stopped taking anxiolytic medication and two thirds reported an elimination of their anxiety symptoms. It is ...

A meta-analysis was conducted to examine the effects of exercise on anxiety. Because previous meta-analyses in the area included studies of varying quality, only randomized, controlled trials were included in the present analysis. Results from 49 studies show an overall effect size of -0.48, indicating larger reductions in anxiety among exercise groups than no-treatment control groups. Exercise...

Although cannabis derivatives produce clear subjective motivational responses in humans leading to drug-seeking behaviour, the reinforcing attributes of these subjective effects are difficult to define in experimental animals. The aim of this study was to examine how exposure to chronic unpredictable stress (CUS) will affect reward function and anxiety after acute administration of Delta(9)-tet...

Seventy patients suffering from primary anxiety state were selected for this clinical trial. They were randomly assigned to Prochlorperazine (Group I) and other drugs eg., Chlordiapoxide etc. (Group II). Hamilton's anxiety scale was employed to rate the anxiety. With the 4 weeks of therapy there was significant fall in score in both the groups of patients but the fall in score is more in Group ...

OBJECTIVE To examine the recorded indication for antipsychotic prescriptions in UK primary care. DESIGN Cohort study. SETTING Primary care. PARTICIPANTS Individuals prescribed antipsychotics between 2007 and 2011. MEASURES The proportion of individuals prescribed antipsychotics with a diagnosis of (1) psychosis and bipolar disorder, (2) other diagnoses including depression, anxiety and ...

Given the enormous contribution of anxiety disorders to the burden of disease, it is key to optimize their prevention and treatment. In this critical review we assess advances in the pharmacotherapy of anxiety disorders, as well as remaining challenges, in recent decades, the field has seen rigorous clinical trial methods to quantify the efficacy and safety of serendipitously discovered agents,...

Although exposure-based treatments and anxiolytic medications are more effective than placebo for treating anxiety disorders, there is still considerable room for further improvement. Interestingly, combining these two modalities is usually not more effective than the monotherapies. Recent translational research has identified a number of novel approaches for treating anxiety disorders using ag...

The current study investigated the anxiolytic properties of the deep transcranial magnetic stimulation (DTMS) in unipolar major depression using a systematic literature review and meta-analysis. Compared to baseline, large anxiolytic and antidepressant outcomes were obtained after 20 daily sessions of high-frequency DTMS according to data from six open-label studies with 95 patients. Unlike the...