The first aim of the research conducted as part of this thesis was to investigate the expression and activities of 11PHSD enzymes in porcine mural granulosa cells and COCs from small, medium and large antral follicles, as well as from ovarian cysts. Both cloned lipHSD enzymes (11 PHSD 1 and 11PHSD2) were expressed in porcine granulosa cells however the results of the expression studies in COCs ...

the aim of this study was to investigate the in vitro developmental competence of isolated pre-antral follicles derived from vitrified ovaries in the presence of coenzyme q 10 (coq 10 ) . mice pre-antral follicles derived from fresh and vitrified-warmed ovarian tissues were in vitro cultured individually in α-mem medium supplemented with or without coq 10 , followed by adding human chorionic go...

BACKGROUND There is substantial evidence both in humans and in animals that a prolonged reduction in plasma thyroid hormone concentration leads to reproductive problems, including disturbed folliculogenesis, impaired ovulation and fertilization rates, miscarriage and pregnancy complications. The objective of the present study is to examine the consequences of chronic hypothyroidism, induced in ...

AMH is synthesized specifically by granulose cells of developing ovarian preantral and small antral follicles. Circulating AMH levels in women with PCOS are 2to 3-fold more compared to ovulatory women with normal ovaries [6,7], which denotes to the 2to 3-fold rise in the count of small follicles detected in PCOS. The excessive AMH has been hypothesized to decrease follicle sensitivity to FSH in...

background: this study aimed to evaluate the strength of anti?mullerian hormone (amh) and follicle stimulating hormone (fsh) in reflecting the antral follicle count (afc) in infertile females. materials and methods: this cross?sectional study was conducted on 160 females, visiting infertility clinic for assisted reproduction. serum samples collected on the 3rd day of the cycle were assayed for ...

27:212–216. van Disseldorp J, Lambalk CB, Kwee J, Looman CW, Eijkemans MJ, Fauser BC, Broekmans FJ. Comparison of interand intra-cycle variability of anti-Mullerian hormone and antral follicle counts. Hum Reprod 2010;25:221–227. Var T, Batioglu S, Tonguc E, Kahyaoglu I. The effect of laparoscopic ovarian cystectomy versus coagulation in bilateral endometriomas on ovarian reserve as determined b...

Recent studies indicate that the antral follicle population may be of paramount importance to improve reproductive performance in cows. There is already an agreement that the antral follicle count (AFC; follicles ≥3 mm in diameter) is a highly variable trait among animals, but with high repeatability in the same individual. Thus, females can be classified into low, intermediate or high AFC. Sev...

background: cryopreservation of pre-antral follicles is a hopeful technique to preserve female fertility. the aim of the present study was to evaluate reactive oxygen species (ros) and total antioxidant capacity (tac) levels of mouse vitrified pre-antral follicles in the presence of alpha lipoic acid (ala). methods: isolated pre-antral follicles (140–150 µm in diameter) were divided into vitrif...