351 Prevalence of Thyroid Peroxidase Autoantibodies (ANTI-TPO) in Women with Autoimmune Connective Tissue Diseases (ACTD) Georgios Papadopoulos, MD, Anastasia Vakaloudi, PhD, Eirene Koutsika, MD, Ekarerini Anastasiou, MD, and Asimoula Koteli, MD. Immunology Laboratory, General Hospital Agios Pavlos, Thessaloniki, Greece. Background: Chronic autoimmune thyroiditis, manifested by positive test fo...

Background and Aim: Spontaneous abortion is the most common pregnancy complication with no reasonable causes in most cases. Some research imply the role of anti-thyroid antibodies (e.g. anti TPO-Ab and anti TG-Ab) that can cause spontaneous abortion. In the present study, the association between abortion and presence of antithyroid antibodies in mother’s serum was assessed. Methods: In this cas...

This review summarizes data on the incidence of autoimmune diseases and examines prevalence antithyroid antibodies in extrathyroid diseases. In world, about 5–7% population suffers from one or another type Among six most common diseases, thyroid associated predominate. The high raises questions potential role course It is believed that are result interactions between triggers, autoantigens, gen...

This study aims to investigate the relationship between thyroid peroxidase antibody (TPO) and function tests (TSH, T3 T4) in patients with type 2 diabetes mellitus (T2DM). Ninety women men, ages ranging 35-65 years weighing 60-80 kgs, were selected for this study. They classified into three groups: G1 included 15 healthy control group, G2 had15 T2DM G3 had 60 hypothyroidism. Blood samples colle...

Background. Postpartum thyroiditis (PPT), characterized by transient hyperthyroidism and transient hypothyroidism, occurs in 5–9% of women. It is accompanied by the presence of circulating antithyroid peroxidase antibodies (TPOAb) which have been associated with an increase in depressive symptomatology compared with TPOAbnegative women. Aim. To assess the frequency and nature of the syndrome in...

background: premature ovarian failure (pof) is a disorder of multi causal etiology. autoimmunity has been proposed as a mechanism for some cases of ovarian follicle dysfunction which is evident in pof. the aim of this study was to identify the level of auto-antibodies in pof and familial pof patients. materials and methods: in this study, auto-antibodies including anti-ovarian antibody (aoa), a...

Background Premature ovarian failure (POF) is a disorder of multi causal etiology. Autoimmunity has been proposed as a mechanism for some cases of ovarian follicle dysfunction which is evident in POF. The aim of this study was to identify the level of auto-antibodies in POF and familial POF patients. MaterialsAndMethods In this study, auto-antibodies including anti-ovarian antibody (AOA), anti ...

OBJECTIVE Interferon therapy of HCV infected patients is associated with development of thyroid dysfunctions. Patients with pretreatment presence of antithyroid peroxidase (TPO-Ab) are at greater risk. This study, probably the first in Pakistan, was planned to determine TPO-Ab in sera of treatment-naive local HCV patients. Setting. Centre for Nuclear Medicine (CENUM), Mayo Hospital, Lahore. P...

We evaluated the prevalence of autoimmune thyroiditis in a random sample of 1188 schoolchildren aged 8-13 years with normalized iodine intake in the Islamic Republic of Iran. The prevalence of goitre was 39.6%; the majority had palpable but non-visible goitre. Of a subsample of 500 children, median urinary iodine excretion (18/8 microg/dL) indicated normal iodine intake. Thyroid peroxidase (TPO...