The reaction mechanisms by which antioxidants can exert their activity are: hydrogen atom transfer (HAT), proton coupled electron transfer (PCET), sequential proton loss electron transfer (SPLET), single electron transfer proton transfer (SET-PT), radical adduct formation, and sequential proton loss hydrogen atom transfer. The antioxidative activity of different compounds (flavones, flavonols, ...

Pyrrolidines type 2,4-disubstituted (alkyl, aryl or heteroaryl)-6,8-dioxo-3,7-diazabicyclo [3.3.0] octanes (8a-d) were successfully synthesized by an efficient one pot 1,3-dipolar cycloaddition of azomethine ylides (in situ generated from the reaction of aromatic aldehydes and methyl ester of α-amino acids) with dipolarophile (N-phenylmaleimide). The reaction of compounds 8a-d with hydrazine in...

BACKGROUND The study of phenolic compounds profiles and antioxidative activity in ginseng fruit, leaves, and roots with respect to cultivation years, and has been little reported to date. Hence, this study examined the phenolic compounds profiles and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free-radical-scavenging activities in the fruit, leaves, and roots of Korean ginseng (Panax ginseng Meyer) a...

BACKGROUND Patients suffering from chronic kidney disease (CKD) are exposed to increased oxidative stress and disturbances manifesting in the enzymatic and non-enzymatic antioxidative defence system. The object of the research was to assess the differences between conservative treatment, peritoneal dialysis and haemodialysis in moderating cellular antioxidative agents. METHODS The group exami...

objectives: eriobotrya japonica belongs to the rosaceae. studies have shown that the flowers of this plant are rich in phenolic and flavonoid compounds. accorrdingly, the evaluation of antioxidative effects of eriobotrya japonica flower extract (ejfe) have been performed in vitro. material and methods: in this study, to investigate the influences of components of ejfe on its antioxidative activ...

The potential antisenescence effect of eight synthetic urea compounds was investigated in excised barley (Hordeum vulgare L.) leaves which were induced to senesce by incubation in complete darkness. The compounds having uncyclic ureido group showed higher chlorophyll retention activity than those with cyclic ureido group. Compounds 1, 6 and 4PU had long-term protecting effects on chlorophyll de...

Potential antioxidative activities of three series of newly synthesized N-oxides were studied. Individual components in each of the series differed in the lipophilicities and number of free radical scavenging groups. Various methods were used to determine their antioxidative efficiencies: Prevention of erythrocyte membrane lipid oxidation induced by UV irradiation and chromogen experiments in w...

Two xanthones and two caged-prenylated xanthones, named cochinchinones A-D, respectively, and a synthetically known caged-prenylated xanthone, together with seven known compounds were isolated from the roots of Cratoxylum cochinchinense (Lour.) Blume. Their structures were assigned on the basis of analyses of spectroscopic data. Some of the compounds exhibited effective antioxidative properties.

Formation of small and highly reactive oxygen species (ROS) is normal phenomena in living cells. The Reactive Oxygen Species cover free radical such as superoxide (O2 ̅ ), hydroxyl (OH), perhydroxy (HO2 ̅ ) and alkoxy (RO) and non-radicals like, hydrogen peroxide (H2O2) and singlet oxygen ( O2). Their formation and reactivity is well established and found to be tightly regulated. ROS level exceed...

INTRODUCTION Acne vulgaris is a common chronic inflammatory disease of the pilosebaceous unit triggered by Propionibacterium acnes. A bakuchiol, Ginkgo biloba extract, and mannitol (BGM) complex has been developed to provide patients with acne with a specific dermocosmetic to be used adjunctively with conventional treatments. OBJECTIVE The aim of these studies was to assess the antibacterial,...