GH and IGF-I concentrations decline with age. Age-related changes appear to be linked to decreases in the anabolic hormones, GH and IGF-I. The aim of this study was to investigate the antioxidant, anabolic, and metabolic effects of the IGF-I replacement therapy, at low doses, in aging rats. Three experimental groups were included in this protocol: young healthy controls (17 wk old); untreated o...

Background: Varicocele occurs in approximately 15 to 20% of the general male population and it is the most common cause of poor semen production and decreased semen quality. Clinical studies have show that varicocele surgery can improve semen quality. The aim of this study was to evaluate if antioxidant therapy adds any extra benefit to standard inguinal varicocelectomy in improvement of sperm ...

UNLABELLED Reactive oxygen species (ROS) overgeneration is involved in the pathogenesis of hepatitis C. The aim of this study was to evaluate the antioxidant status in the blood of HCV infected patients treated or not with standard therapy before and after supplementation of vitamins E, C and zinc. Biomarkers of oxidative stress were evaluated in the blood of three groups of patients: group 1 -...

background: acute pancreatitis (ap) refers to afflicted inflammation of pancreas with unfavorable adverse effects and developed multiple organ failures. unfortunately, there is not a certain therapeutic method for this disease. oxidative stress has a serious role in the pathogenesis of ap. thus, decreasing of oxidative stress may prevent induction and progression of ap. punica granatum l. has b...