CONTEXT Oxidative damage due to oxidative stress is the failure of the cell's defense against the deleterious effects of harmful agents by means of its numerous autoprotective mechanisms. oxidative stress is a key impairment induced by various conditions, including atherosclerosis, hypertension, ischemia-reperfusion, hepatitis, pancreatitis, cancer, and neurodegenerative diseases. EVIDENCE AC...

Antioxidant compounds inhibit formation of free radicals, chelate catalytic metals, and scavenge free radicals in biological systems. In addition, antioxidants play a decisive role in prevention of numerous physiological dysfunctions, cancers, and metabolic disorders. This study sought to evaluate the antioxidant capacity and cytotoxic effect of grape seed extract (GSE), crocin (CRO), and pheny...

Introduction: Oxidative stress is one of the important pathologic factors involved in the pathogenesis of neurodegenerative diseases. Antioxidants as neutralizing agents of free radicals are one of the treatment options for these diseases and antioxidant agents that can pass through blood brain barrier have beneficial effects. In the present research, the antioxidant effect of a new iron ...

Background and objectives:Alzheimer’s disease (AD) is a neurodegenerative disorder. Nowadays, many investigations are performed to find new drugs for AD and medicinal plants are considered as one of the most important sources for developing new drugs. According to the role of oxidant agents and acetylcholinesterase enzyme (AChE) in AD, plants with antioxidant and AChE inhibitio...

Oxidative stress due to an overwhelming release of reactive nitrogen / oxygen species (R(N)OS) is held largely responsible for sepsis-induced organ failure and mortality. Excessive R(N)OS production is neutralized by endogenous antioxidants (reduced glutathione (GSH), enzymes such as GSH peroxidase, and antioxidant vitamins) but this antioxidant potential becomes dramatically reduced in sepsis....

Antioxidant agents against reactive oxygen species can be used for several cosmetic and medicinal applications. This study's objective was to evaluate the antioxidant activities of Polytrichastrum alpinum (Hedw.) G. L. Sm. (Polytrichaceae), an Antarctic moss species collected from King George Island (Antarctica). The identification of the moss species was performed on the basis of morphological...