A longitudinal population study of 1462 women aged 38-60 was carried out from 1968-9 to 1980-1 in Gothenburg, Sweden. The initial and follow up examinations included questions concerning history of diabetes and antihypertensive treatment. A considerably increased risk of developing diabetes was observed for subjects with hypertension taking diuretics (895 patient years), subjects taking beta bl...

In this 10-minute consultation by Mohammed Awais Hameed and colleagues (BMJ 2016;354:i3268, doi:10.1136/bmj.i3268), the final sentence of the first paragraph under the heading “Discuss risk” should not have read: “For example, ‘In a population of 100 people aged 40-69, with every 2 mm Hg rise in blood pressure, 10 people are at risk of dying from a stroke and seven people are at a risk of dying...

Interactions between drugs and antihypertensive agents can result in either increased or decreased antihypertensive effects. These interactions may be pharmacokinetic or pharmacodynamic in type, resulting in either altered plasma drug concentrations or altered drug effects at similar plasma concentrations. Drugs may limit the absorption of antihypertensive agents, alter their metabolism through...

BACKGROUND Stroke is a leading cause of death and disability; worldwide it is estimated that 16.9 million people have a first stroke each year. Lipid-lowering, anticoagulant, and antihypertensive drugs can prevent strokes, but may be underused. METHODS AND FINDINGS We analysed anonymised electronic primary care records from a United Kingdom (UK) primary care database that covers approximately...

OBJECTIVE To evaluate the frequency of oral antihypertensive medication preceding the increase in blood pressure in patients in a university hospital, the drug of choice, and the maintained use of antihypertensive medication. METHODS Data from January to June 1997 from the University Hospital Professor Edgard Santos Pharmacy concerning the prescriptions of all inpatients were used. Variables ...