DESCRIPTION GLUCOPHAGE (metformin hydrochloride) Tablets and GLUCOPHAGE XR (metformin hydrochloride) Extended-Release Tablets are oral antihyperglycemic drugs used in the management of type 2 diabetes. Metformin hydrochloride (N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. The structura...

Diabetes mellitus (DM) is a serious worldwide problem related to human hyperglycemia. Thus, herbal preparations with antihyperglycemic properties especially leaf extracts of hydroponic Stevia rebaudiana (SR) would be useful in hyperglycemia treatment. The antihyperglycemic potential of this medicinal plant grown using hydroponics methods has been evaluated. Significant reduction of some biochem...

The aqueous extract of Clitoria ternatea Linn leaves were screened for its antihyperglycemic activity in streptozotocin induced and glucose induced diabetic rats in doses of 100, 250 and 500 mg/kg body weight. At a dose of 100 mg/kg (bw), aqueous leaf extract did not produce significant antihyperglycemic activity, however a doses of 250 mg/kg of Clitoria Ternatea leaf extracts significantly red...

Silybum marianum (L) Gaertn (milk thistle) seeds, Urtica dioica L (nettle) leaves, and Boswellia serrata (olibanum gum) resin are used traditionally by Iranian diabetic patients. The aim of this study was to evaluate the antihyperglycemic effects of these herbs in an herbal formulation in patients with type II diabetes mellitus. Sixty patients diagnosed as type II diabetes mellitus with fasting...

Rao C. A. et al; (2003) evaluated hypoglycemic and antihyperglycemic activity of ethanolic fraction of fruits of Terminalia pallid at different doses in normal and alloxan diabetic rats. The ethanolic extract of fruits of TP at a dose of 0.5 g/kg b.w. could produce a significant fall in blood glucose levels by about 24% in diabetic rats, after 5 h of treatment. But none of these extracts could ...

AIMS/INTRODUCTION We compared clinical characteristics in patients with type 2 diabetes for whom different antihyperglycemic agents were prescribed as monotherapy or combination therapy by diabetes specialists in Japan. MATERIALS AND METHODS Prescription data for 2005, 2008 and 2011 from diabetes specialists' patient registries identified variables related to prescription of different antihyp...

BACKGROUND Xanthium indicum stem is used in folk medicine of Bangladesh to control sugar in diabetic patients and to alleviate pain. The objective of the study was to evaluate antihyperglycemic and antinociceptive activity of methanolic extract of Xanthium indicum stems (XISE) in mice. METHODS Antihyperglycemic activity was measured by oral glucose tolerance tests in glucose-loaded Swiss albi...

BACKGROUND Alternanthera sessilis is used by folk medicinal practitioners of Bangladesh for alleviation of severe pain. The objective of this study was to scientifically analyze the analgesic (non-narcotic) property of aerial parts of the plant along with antihyperglycemic activity. METHODS Antihyperglycemic activity was measured by oral glucose tolerance tests. Analgesic (non-narcotic) activ...

The present study aimed to assess the hypoglycemic and antihyperglycemic activity of fruit methanolic extract of Luffa cylindrica fruits. The effect of methanolic fruit extract on oral glucose tolerance and its effect on normoglycemic rats were studied. The same was tested for antihyperglycemic activity in alloxan induced hyperglycemic rats at the two dose levels 200 and 400 mg/kg body weight p...