conclusions compared with acarbose or metformin monotherapy, the addition of acarbose to metformin had superior antihyperglycemia efficacy and provided an efficacious and safe alternative for the treatment of type 2 diabetic rats. acarbose/metformin reduced the fasting blood glucose and glycated hemoglobin without significant changes in serum visfatin levels. background diabetes mellitus is a c...

Introduction Diabetes mellitus is a chronic metabolic disease which involves nearly all organs of human body, and is an important challenge of healthcare system in throughout the world. It is a prominent risk factor for cardiovascular disorders such as hypertension and atherosclerosis, renal failure, neuropathies, eye and skin complications. Hyperglycemia induced over production of reactive spe...

Diabetes merupakan penyakit kronis yang terjadi di saat insulin diproduksi oleh tubuh tidak bisa digunakan secara efektif maupun organ pankreas mengalami masalah dimana dapat sebagaimana mestinya. Mellitus dibagi menjadi dua jenis yaitu IDDM (DM tipe I) dan NIDDM 2. Kebaruan penelitian ini menguji efektivitas nonherbal kemangi sebagai antihiperglikemia pada tikus diabetes terindukasi streptozot...

Cardiovascular disease is the leading cause of death in patients with diabetes. However, identifying mechanisms of disease progression has proven difficult as diabetes involves dysfunction of numerous pathways including cellular signaling and mitochondrial capacity. This results in the alteration of circulating hormones and nutrients that can lead to inflammation, oxidative stress, endoplasmic ...