the series of 3-(substitutedphenyl)-n-(4h-1,2,4-triazol-4-yl)acrylamide compounds were prepared byreaction of 4-amino-1,2,4-triazole with acetyl chloride followed by claisen-schmidt condensation reactionwith different aromatic aldehydes. the structures of new compounds were confirmed by ir, 1h-nmr and13c-nmr spectral data. anti-bacterial and anti-fungal activities were evaluated and compared wi...

background candida species are normal microflora of  oral cavity, vagina, and gastrointestinal  tract. they are the third most prevalent cause of pediatric health care–associated  bloodstream fungal infection. this study aimed to provide an epidemiological feature of candidiasis and also presents an antifungal susceptibility profile of clinical candida isolates among children. materials and met...

background: lactic acid bacteria (lab) isolated originally from sourdough are probably the best candidates as biopreservatives, because they are well adapted to the non-aseptic conditions in sourdough fermentation. the aim of the present study was to study antifungal properties of a dominant endogenous lab isolated from whole barley sourdough. methods: whole barley flour from a mixture of barle...

introduction: natural products have been the most successful source of potential drug leads. one of them is lichens, which have been used since antiquity as natural sources of drugs. the aim of this study was to investigate the antibacterial and antifungal activity of different extracts of the iranian lichens in ilam province. methods: the aqueous, acetone, and methanol extracts of 6 lichen spe...

Background: Candida species are an important cause of opportunistic infection in the oral cavity of immunocompromised patients. Various antifungal agents have been used for the treatment of oral candida infection. Tea tree oil is a herbal product which is known to have broad antifungal properties. Objective: To compare the antifungal efficacy of 1% tea tree oil, 1% clotrimazole, and 0.2% chlorh...

In Japan, only a few antifungal agents have been approved for children, but in actual clinical practice, various antifungal agents used in adults are administered to pediatric patients with invasive fungal infections (IFIs). However, the pediatric dosages of some antifungal agents are not indicated in the package inserts or mentioned in the Japanese Mycology Study Group 2007 Guidelines for Mana...

Trichophyton violaceum is an anthropophilic fungus. Dermatophytosis (Tinea) is fungal infection that can infect the scalp, glabrous skin, and nails. In general, Tinea can be spread by skin-to-skin contact or bathroom or floor materials. The treatments of Tinea need antifungal medication and good hygiene environment. The effective antifungal medication and infection prevention, and the creation ...

This work analyses the chitin-binding and catalytic domains of the human macrophage chitotriosidase and investigates the physiological role of this glycoside hydrolase in a complex mechanism such as the innate immune system, especially its antifungal activity. Accordingly, we first analyzed the ability of its chitin-binding domain to interact with chitin embedded in fungal cell walls using the ...

Natural dye extracted from aerial parts of Barleria prionitis and different kinds of textile fabrics dyed with the natural dye were investigated for their antifungal activity. Antifungal activity of natural dye and dyed fabrics was assessed against standard strains of five fungi namely Aspergillus flavus, A. niger, A. parasiticus, Fusarium moniliforme and Penicillium canescens using agar-we...