objective(s): anti-epileptic drugs (aeds) have the potential to affect fetal development throughout pregnancy. considering the broad therapeutic indications of pregabalin (pgb), its potential teratogenic effects and the levels of homocysteine have been studied.   materials and methods: timed-pregnant mice received one of three doses of pgb (20, 40 or 80 mg/kg/day) or the vehicle control during ...

Anticonvulsants are a diverse group of pharmaceuticals used in the treatment of epileptic seizures. The goal of an anticonvulsant is to suppress the rapid and excessive firing of neurons that start a seizure. The use of current antiepileptic drugs has been questioned due to the non selectivity of the drugs and the undesirable side effects posed by them. The search for antiepileptic compounds wi...

Cutaneous adverse reactions to antiepileptic drugs: 17 cases at the Dermatology Department of Arrazi Hospital in Marrakech

Phenytoin is an antiepileptic agent that has been in clinical use for approximately 80 years, particularly due to its and antineuralgic activity antiarrhythmic effects. also become increasingly widely used recent years various applications, including wound healing, migraine, dizziness, myocardial infarction, bipolar disorder, types of ulcer, burns. Vertigo/dizziness frequently seen children. Nu...

Aim: Little is known about the consumption of antiepileptic drugs in pregnancy in the Czech Republic, particularly for newer agents. In our previous paper, we discussed long-term trends in the utilization of antiepileptic drugs during pregnancy in a group of 235 women between 1991–2006. Currently, we continue to investigate the long-term trends in antiepileptic drug use in pregnant women. Metho...