Background and objectives: Calamus rotang is used in traditional medicine. Regarding the previous phytochemical screening of methanol extract of Calamus rotang L. fruits (MCR), this study was performed to find out the antidiarrheal and hypoglycemic effects of the experimented extract in rodents. Methods: Castor oil induced diarrheal test...

introduction: artemisia dracunculus l. belongs to asteraceae family, and is a medicinal plant widely used in traditional medicine as a remedy for gastrointestinal disturbances. this study was undertaken to evaluate the effects of essential oil of a. dracunculus (eoad) on the rat alimentary tract. methods: the eoad was extracted by clevenger apparatus using hydrodistillation. ld50 was calculated...

BACKGROUND The fruit of Rosa moschata has traditionally been used for the treatment of abdominal spasm and diarrhoea. Therefore, the aim of this study was to investigate mechanism(s) responsible for its medicinal use in gut spasm and diarrhea. METHODS Hydro-methanolic extract of Rosa moschata (Rm.Cr) was studied in isolated rabbit's jejunal preparations for possible antispasmodic activity. Ba...

Wood creosote has long been used as an antidiarrheal agent, but its mechanism of action is not well understood. To elucidate the mechanism of its antidiarrheal activity, we have addressed questions whether it inhibits fluid secretion induced by Escherichia coli heat-stable enterotoxin (STa) in rabbit jejunum in vivo, and whether it inhibits muscle contraction of isolated rabbit ileum ex vivo. W...

To determine whether the antidiarrheal action of opiate drugs in humans is due to enhanced intestinal absorption rates, as suggested by recent experiments in animals, or is due to altered intestinal motility, as traditionally thought, we studied the effect of therapeutic doses of codeine on experimental diarrhea and on the rate of intestinal absorption of water and electrolytes in normal human ...

objectives: mentha longifolia l. (lamiaceae) is an annual herb that is used in the iranian traditional medicine for treating stomach and intestinal disorders. the purpose of this study was to determine the protective effect of m. longifolia on experimental diarrhea in a rat model. materials and methods: the antidiarrheal activity of essential oil of m. longifolia (20-80 mg/kg) was investigated ...

Wood creosote, a mixture of guaiacol, creosol and related compounds, has long been used as an antidiarrheal agent. The goal of our study was to investigate the antisecretory effect of wood creosote and to compare it to the effect of loperamide, a synthetic opioid widely used in the treatment of diarrhea. Experiments were performed in rat jejunal and colonic mucosal sheets, mounted in modified U...

This study is aimed at evaluating the phytochemical constituents and the antidiarrheal activities of the acetone extract of Acacia sieberiana stem bark. The phytochemical screening was carried out to identify the active constituents present in the acetone extract, and the acute toxicity test was also carried to determine the safety limit of the extract. Gastro intestinal motility and castor oil...

BACKGROUND OF THE STUDY As a widely used traditional medicine, Galla Chinensis is rich in tannins. However, there are few detailed studies about pharmaceutical preparations of Galla Chinensis tannin extract (GTE). In the present experiments, for better application and to investigate the possibility that Galla Chinensis tannin extract can be used as an antidiarrheal drug, we prepared Galla Chine...