TAN 1057-resistant Staphylococcus aureus and Escherichia coli strains were selected to elucidate the mechanism of resistance and the mode of action of this dipeptide antibiotic. Cell-free translation with isolated ribosomes and S150 fractions from sensitive and resistant S. aureus strains demonstrated that alterations in the ribosomes contribute to the resistance of the bacteria.

OBJECTIVE. The purpose of this narrative review was to evaluate the antimicrobial activity garlic (_Allium sativum_), thyme (_Thymus vulgaris_), oregano (_Origanum vulgare_), turmeric (_Curcuma longa_), rosemary (_Rosmarinus officinalis_) and cinnamon (_Cinnamomum _species) for treatment antibiotic-resistant strains _Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Esche...

Pathogenic microbiology investigators have a responsibility to consider the public health implications of their research, including the experimental introduction of antibiotic resistance markers that could influence the treatment of infectious diseases. Furthermore, the reviewers for Infection and Immunity as well as other scientific journals are asked to evaluate submitted manuscripts for the ...

Antibiotics have shown a proven efficiency profile in therapy against some infectious agents for several decades. Nevertheless, a large-scale spreading of antibiotics in the environment, and emergence of resistant or even multi-resistant pathogenic bacterial strains has become a general concern promise to even further increase. Besides therapeutic applications, antibiotics are often used as a s...

This study aimed to determine the antibiotic and bacteriocin sensitivity of Listeria monocytogenes strains isolated from animal derived foods. With disc diffusion assay, all fourteen L. monocytogenes strains were susceptible to the antibiotics, including penicillin G, vancomycin, tetracycline, chloramphenicol, rifampicin, erythromycin, gentamicin and trimethoprim. However, the percentage...

Naturally occurring strains of staphylococci which are resistant to chloramphenicol (CM) inactivate this antibiotic. One of the inactivation products of CM showed the chromatographic behavior of 3-acetoxychloramphenicol. Induction of resistance occurred after prior exposure to subinhibitory concentrations of the antibiotic. The resistance of induced populations, as well as CM-inactivation abili...

Emergence of antibiotic-resistant bacteria threatens the continued efficacy of many critical drugs used to treat serious infections. What if such resistant organisms could also act as altruists and "share" their resistance with sensitive cohorts without any actual genetic exchange? We competed resistant strains that differ solely in their ability to secrete a plasmid-encoded beta-lactamase. Sen...