نتایج جستجو برای: anti tumor
تعداد نتایج: 748612 فیلتر نتایج به سال:
Background: Nowadays, dendritic cells (DC) are used for tumor immunotherapy as they can induce immune responses against tumor cells. In this research, we comprehensively studied the maturation stimulus addition, PHA-activated T-cell (PHA- TCM) conditioned medium, autologous monocyte-conditioned medium (MCM) and TNF-α for their ability to promote uniformly mature dendritic cells that eli...
background: the use of dendritic cells (dcs) as a cellular adjuvant provides a promis-ing approach in immunotherapy of cancer. it has been demonstrated that listeria mono-cytogenes activated dcs pulsed ex vivo with tumor antigens trigger a systemic th1-biased specific immune response and a single dose of this vaccine will cause a consider-able anti tumor immunity. objective: the present study w...
Background: Noradrenaline (NA), the principal neurotransmitter released from sympathetic nerve terminals, influences T-cell maturation, not only directly in developing T cells, but also indirectly, by acting on the thymic nonlymphoid cells. In vitro and in vivo studies have demonstrated the anti-proliferative, anti-migratory, antiangiogenic and cytotoxic properties of propranolol, β-AR blocker,...
Abstract Glioblastoma is the most aggressive primary brain tumor and adults poorly immunogenic. Treatment options for recurrent glioblastoma after standard of care chemoradiation are limited Several immunotherapeutic strategies including peptide vaccination immune checkpoint inhibition have so far failed to improve survival except from potentially regorafenib, no other agent has demonstrated su...
Objective(s):IL-12 as an anti-tumor cytokine and IL-33 a novel identified cytokine with both pro- or anti-tumor activities, play important roles in response against tumor cells. Our aim was to evaluate the IL-12 and IL-33 levels and single nucleotide polymorphisms (SNP) in their genes in patients with breast cancer. Materials and Methods:Blood samples were collected from 100 patients with breas...
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is is most common form ofimmune-mediated encephalitis with prominent neurologic and psychiatric features at disease onset. We describe a 16 years old patient who presented with fever and status epilepticus. His MRI sequences was normal. Anti-NMDAR antibodies were detected in the CSF. MRI, CT and other studies didn,t show any tum...
در مواردی سیستم ایمنی بدن باعث بروز بیماریهای ایمنی مانند آنمی همولتیک نوزادان hdn می شود. تنها راه پیشگیری ایزوایمونیزاسیون rh ، ،تجویز پارتابولین (anti-d) به مادران rh منفی بعد از تولد نوزاد rh مثبت می باشد. پیشگیری از آلوایمونیزاسیون ناشی از ترانسفوزیون و درمان itp از دیگر اندیکاسیونهای تجویز anti-d می باشد. روش acid elution برای شناسایی میزان fmh جهت تصحی...
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