background: the cutaneous leishmaniasis (cl) has been occurred in dehbakri county, located 46 km of bam dis­trict, kerman province since 2004–2005. phlebotomus papatasi is an important vector of zoonotic cutaneous leishmanisis (zcl) as well as sand fly fever and p. sergenti is considered as main vector of anthroponotic cutaneous leishmaniasis (acl) in iran. there are several measures for vector...

leishmaniasis has long been known as a significant public health challenge in many parts of iran. phlebotomus pa­patasi and p. sergent i are the vectors of zoonotic cutaneous leishmaniasis and anthroponotic cutaneous leish­maniasis respectively, and 5 species of sand flies including p. kandelakii , p. neglectus , p. perfiliewi , p. keshishiani and p. alexandri are considered as probable vectors...

An in vitro investigation was carried out to assess how the lipopeptide biosurfactant (LPB) produced by Acinetobacter junii B6 affects Leishmania tropica infection and associated cytokine gene expression macrophages infected with L. tropica. Glucantime® (meglumine antimoniate, MA) LPB were investigated for their leishmanicidal effect, alone combination (LPB + MA), using a colorimetric test macr...

Background: Cutaneous leishmaniasis (CL) is a major world problem. Several types of treatment regimens have been suggested. Imiquimod demonstrated a leishmanicidal activity by increasing local cytokine production. The aim of this study was to determine the efficacy of topical 5% imiquimod with cryotherapy vs. intralesional meglumine antimoniate (MA) in treatment of anthroponotic (dry type) CL. ...

BACKGROUND A vaccine consisting of a single dose of whole-cell autoclave-killed Leishmania major (ALM) mixed with BCG was assessed in comparison with BCG alone against anthroponotic (human to human transmission) cutaneous leishmaniasis in a randomised double-blind trial in Bam, Iran. METHODS 3637 schoolchildren, aged 6-15 years, with no history of cutaneous leishmaniasis and no response to a ...

To the Editor: Recent reports from Afghanistan have focused on the current status of war-and refugee-related anthroponotic cutaneous leishmaniasis (ACL), caused by Leishmania tropica, in Kabul City, refugee camps, and Fayzabad City (Badakhshan Province) (1–4). In central Asia, ACL is transmitted mainly by the sandfly Phlebotomus sergenti in urban or peri-urban environments (5). Zoonotic cutaneo...

Leishmaniasis, a globally prevalent parasitic disease occurs in three forms viz., visceral, cutaneous and mucocutaneous, transmitted by the bite of infected female Phlebotomus sandflies. Visceral leishmaniasis (VL) has 100 per cent fatality rate, if left untreated. India has the largest burden of this disease. HIV infection is also increasing worldwide and several reports indicate rising trend ...