Anophthalmia in the Syrian hamster was found to result from an extensive degeneration of retinal tissue and tissues derived from the retina. Eyes of affected animals were normal at the twelfth day of gestation (the average gestation period in the Syrian hamster is 16 days). However, the retina of these eyes showed rapid and extensive degeneration during the first two weeks after birth. In adult...

PURPOSE To report the results of a simple outpatient method for soft tissue socket expansion in young children with congenital anophthalmos. METHODS Seventeen congenital anophthalmic sockets of 15 infants of a mean age of 4.2±4.4 months were fitted with specially designed serial solid acrylic shapes or hydrogel expanders using cyanoacrylate for eyelids closure when using the latter. RESULTS...

Lenz microphthalmia syndrome was first described by Lenz et al in 1955. The cardinal features of the syndrome are microphthalmia or anophthalmos, narrow shoulders, other skeletal anomalies, and dental and urogenital malformations. Here we present a case of Lenz microphthalmia syndrome who shows the typical characteristics and, additionally, dysgenesis of the corpus callosum associated with dila...

Past Ocular History  Congenital cataracts OU  Chronic angle closure glaucoma OS  Anophthalmos OD  Pseudophakia OS Ocular surgery OD  Needling of congenital cataract 1938  Enucleation 1954  Secondary orbital implant 4/2011 Ocular surgery OS  Needling of congenital cataract 1938  DSAEK/Phaco/Intraocular lens x 2/Anterior vitrectomy 2/2007  Ahmed valve Seton model FP-7 with scleral patch...

A male infant was born with a bilateral cleft lip and/or palate, absent nasal structures, left anophthalmos, right coloboma, and bilateral fifth digit clinodactly. Brain magnetic resonance imaging revealed severe asymmetric hydrocephalus, absent corpus callosum, a suprasellar mass with a high riding third ventricle, and no pituitary gland. He had a normal male karyotype and normal prenatal labo...

AIM To report five children with horizontal jerk nystagmus in whom eye movement recordings in the dark revealed a spontaneous reversal in the direction of the nystagmus beat. Three patients were blind in one eye and were diagnosed as having a manifest latent nystagmus (MLN), and two patients had strabismus and congenital nystagmus (CN). METHODS Eye movements were recorded using DC electro-ocu...