BACKGROUND Mechanistic insights from 3D echocardiography (echo) can guide therapy. In particular, ischemic mitral regurgitation (MR) is difficult to repair, often persisting despite annular reduction. We hypothesized that (1) in a chronic infarct model of progressive MR, regurgitation parallels 3D changes in the geometry of mitral leaflet attachments, causing increased leaflet tethering and res...

M asterful mitral valve (MV) repair demands thorough understanding of integrated mitral apparatus structure and mechanics. One consistently reported feature, the saddle shape of the mitral annulus, was recognized in the process of resolving the contradiction posed by an apparently high prevalence of MV prolapse (MVP) in otherwise healthy individuals: A normal saddle-like shape will show opposit...

The confinement and controlled movement of metal nanoparticles and nanorods is an emergent area within optical micromanipulation. In this letter we experimentally realise a novel trapping geometry near the plasmon resonance using an annular light field possessing a helical phasefront that confines the nanoparticle to the vortex core (dark) region. We interpret our data with a theoretical framew...

We created graphene blisters that cover and seal an annular cylinder-shaped microcavity in a SiO2 substrate filled with a gas. By controlling the pressure difference between the gas inside and outside of the microcavity, we switch the graphene membrane between multiple stable equilibrium configurations. We carried out experiments starting from the situation where the pressure of the gas inside ...

Background—Tricuspid regurgitation (TR) is an important predictor of morbidity and mortality in heart failure. We aimed to examine the 3D geometry of the tricuspid valve annulus (TVA) in patients with functional TR, comparing them with patients with normal tricuspid valve function and relating annular geometric changes to functional TR. Methods and Results—TVA shape was examined by real-time 3D...

We propose and analyze a new type of a resonator in an annular geometry that is based on a single defect surrounded by radial Bragg reflectors on both sides. We show that the conditions for efficient mode confinement are different from those of the conventional Bragg waveguiding in a rectangular geometry. A simple and intuitive approach to the design of optimal radial Bragg reflectors is propos...

in this study a nonlinear asymmetric instability analysis carried out to study primary atomization of annular liquid sheets emanating from the prefilming airblast atomizer using a perturbation method and potential flow assumption. in this direction, firstly governing equations derived according to potential flow assumption and conservation equations while dynamic and static boundary condition a...

rabbitfish is economically valuable teleost species which lives in shallow coastalwaters. two species of rabbit fish have been recognized in southern sea of iran (persiangulf) as namely siganus sutor and siganus javus. in the current study, in order toinvestigate the histology of the annular ligament of the s. javus’ eye, the prepared sectionsof the eyes of twelve healthy specimens were studied...