Chewing improves visuospatial performance through locus coeruleus (LC) activation. The effects of bilateral and unilateral mastication were investigated in subjects showing different degrees asymmetry masseter electromyographic (EMG) activity during clenching pupil size at rest (anisocoria), which is a proxy LC imbalance. Correlations between changes values found males, but not females. Among w...

Background Evaluation of anisocoria including pharmacological testing for Horner's syndrome in the pediatric population is challenging in view of potential serious underlying disease. We describe cocaine test results, outcome of systemic investigation, and long-term follow-up in children with anisocoria. Methods Retrospective review of medical records and phone interview of consecutive pediat...

Miller Fisher syndrome is a variant of Guillain-Barre syndrome characterized by the classic triad of ophthalmoplegia, ataxia, and areflexia. Pupillary involvement is common in MFS and has been reported in 35-42% of MFS patients. Although case reports have discussed isolated ophthalmoplegia as a presentation of MFS, anisocoria and rapid fluctuation of pupillary diameter have not been reported in...

EVALUATING THE “PROBLEM PUPIL” Clinical History.— A 43-year-old woman presented for evaluation of transient anisocoria. Eleven days previously on awakening in the morning, she noted that the right pupil was larger than the left and that she had trouble focusing. About 4 hours later, she saw an optometrist who found the right pupil to be 3 mm in bright light and 6 mm in dim light and the left pu...

Amaç: Anizokori, hayatı tehdit eden kafa içi hadiselerin ilk habercisi olabileceği gibi, sık kullanılan ilaçların yan etkisi olarak da karşımıza çıkabilir. Atropin, skopolamin, amfetamin gibi farmakolojik ajanların sistemik kullanımı genellikle bilateral midriazise yol açarken, nebulizatör ile ipratropium bromürün göze direkt teması tek taraflı midriazis izlenebilir. Bu yazıda, ajana bağlı aniz...

OBJECTIVE To derive a reliable estimate of the frequency of pupil involvement in patients with diabetes-associated oculomotor nerve palsy. PATIENTS AND METHODS In this prospective study, standardized enrollment criteria were employed to identify 26 consecutive patients with diabetes-associated oculomotor nerve palsy who were evaluated in a referral-based, outpatient neuro-ophthalmology practi...