the effects of allium sativum on yogurt formation and subsequent storage (4°c, up to 28 days) on proteolysis, microbial activity, and inhibition of α-amylase, α-glucosidase and angiotensin-i converting enzymes were investigated in vitro. allium sativum yogurt showed higher rates of ph reduction and increment of titrable acid than control during the incubation at 41°c. highest proteolysis was ob...

Introduction: The brain renin-angiotensin system (RAS) has been reported having a pathological role in age-related impairment in learning and memory. Therefore, angiotensin converting enzyme inhibitors (ACEi) are expected to have positive effects on memory. Longtime treatment with captopril (an angiotensin converting enzyme inhibitor) significantly attenuates the age-related impairment in learn...

conclusions traditional medicine based on certain plants could be of beneficial effects in hypertension treatment. results in total, 52 species out of the 135 (39%) screened, gave more than 50% ace inhibition. forty species were found to possess a high ace inhibiting ability and were low in their tannin content. materials and methods in the present study 135 plants used in traditional persian m...

background: early diagnosis of albuminuria and the prevention of its progression to macroalbuminuria and diabetic nephropathy are crucial. angiotensin converting enzyme inhibitors (aceis) and antagonists of angiotensin ii receptors type i (arbs) are currently used as first-line treatment for albuminuria in these patients. the present study was conducted to assess the efficacy of addition of spi...

purpose it is well known that the effects of exercise training gives inter individual differences which might be due to genetic diversity. this study aims to explore the probable relation between angiotensin converting enzyme (ace) alleles and physical fitness parameters in elite athletes. methods twenty-nine national level indian army triathletes who volunteered for the study were taken as sub...

Uncritical Acceptance of Combination Treatment of Angiotensin II Receptor Blocker and Angiotensin-Converting Enzyme Inhibitor in Nondiabetic Renal Disease Trial Results To the Editor: We have just read the published editorial in the present issue of Hypertension by Kaplan1 with great interest. We very much agree with his comments and, in particular, share his concerns with respect to an uncriti...

background: renal ischemia reperfusion (ir) injury has been a major source of concern during the past decades and angiotensin converting enzyme (ace) inhibitors have been successfully used to prevent this injury. there have been some controversial reports about the involvement of katp channels in the mechanism of action of ace inhibitors. in this study, we examined the effect of katp channel bl...

The inhibition of angiotensin converting enzyme by ramipril, ramiprilat, enalapril, enalaprilat, and captopril was studied in the plasma and various tissues (lung, heart, renal cortex, renal medulla) of normotensive rats and spontaneously hypertensive rats. Displacement curves for [3H]ramiprilat were established on each tissue with the converting enzyme inhibitors, and their potencies were expr...

Introduction: The brain renin-angiotensin system (RAS) has been reported having a pathological role in age-related impairment in learning and memory. Therefore, angiotensin converting enzyme inhibitors (ACEi) are expected to have positive effects on memory. Longtime treatment with captopril (an angiotensin converting enzyme inhibitor) significantly attenuates the age-related impairment in learn...

The reaction of the renin-angiotensin system to acute angiotensin converting enzyme inhibition was investigated in a single-blind, crossover study in nine normal volunteers receiving two out of three regimens in random order: the new converting enzyme inhibitor benazepril (20 mg once or 5 mg four times at 6-hour intervals) or enalapril (20 mg). Plasma converting enzyme activity, drug levels, an...