Tm-1, an inhibitor protein of Tomato mosaic virus RNA replication, contains two conserved domains: an uncharacterized domain at its N-terminus and a TIM-barrel-like domain at its C-terminus. The N-terminal domain of Tm-1 has an inhibitory activity and its three-dimensional structure has not been determined. Here, the crystallization and preliminary X-ray diffraction of the N-terminal domain of ...

background: small side branches, albeit less important than their larger counterparts, have not yet received due attention in the literature. nor has there ever been a comparison between drug-eluting stents and bare metal stents apropos side branch occlusion . the aim of this study was to compare the patency of small (≥0.5 and ≤1.5 mm in diameter) side branches with respect to bare metal vs. dr...

Background ART is costly for governments and couples seeking treatment. In addition to any other costs that may arise during treatment, such as medication, consultations and extra procedures, women undergoing IVF experience physical and emotional stress. Furthermore, it is not always possible to get a favorable outcome. Despite all the remarkable scientific advances in modern medicine, traditio...

background gastroesophageal reflux disease (gerd) is a common problem seen in pediatrics and adolescents. the bravo tm ph monitoring system is a capsule that detects and quantifies the severity of reflux disease. this test is also valuable for evaluation of patients with extra-gastrointestinal manifestations of gerd such as asthma, chronic cough, hoarseness, aspiration pneumonia, and pre/post f...

Introduction: To describe the underlay tympanoplasty technique using an acellular dermal graft(AlloDerm) for tympanic membrane (TM) reconstruction in a guinea pig model and to demonstrate the feasibility of the technique using AlloDerm tissue harvested from the prepuce as a source of tissue for future grafting in human TM reconstruction.   Materials and Methods: The prepuce was divided during c...