MicroRNA (miRNA) detection by reverse transcription (RT) quantitative real-time PCR (RT-qPCR) is the most popular method currently used to measure miRNA expression. Although the majority of miRNA families are constituted of several 3'-end length variants ("isomiRs"), little attention has been paid to their differential detection by RT-qPCR. However, recent evidence indicates that 3'-end miRNA i...

Several technologies, such as electromagnetic midsagittal articulography (EMA) or real-time magnetic resonance (RTMRI), enable studying the static and dynamic aspects of speech production. The resulting knowledge can, in turn, inform the improvement of speech production models, e.g., for articulatory speech synthesis, by enabling the identification of which articulators and gestures are involve...

This paper considers inventory models with advance demand information and flexible delivery. Customers place their orders in advance, and delivery is flexible in the sense that early shipment is allowed. Specifically, an order placed at time t by a customer with demand leadtime T should be fulfilled by period t+T ; failure to fulfill it within the time window [t, t+T ] is penalized. We consider...

background: fatigue is a common side effect in cancer patients undergoing radiation therapy (rt). radiation-induced fatigue affects the quality of life, but there is no definitive treatment option. in this study, the weight-loaded forced swim test was performed to assess the effect of coenzyme q10 (coq10) on radiation-induced fatigue. materials and methods: a total of 60 rats were divided rando...

abstract background and objective: highly active antiretroviral therapy (haart) can effectively prevent the progression of hiv-1 replication and increase life expectancy. there are numerous causes of treatment failure and the leading one is drug resistance. thus, we aimed to determine the hiv rt gene drug resistance mutations in patients treated with antiretroviral medications. material and met...

Bovine viral diarrhea virus (BVDV) is a pathogen that infects cattle, and is globally important. It causes substantial financial losses to the livestock industry. In the current study, a one-step reverse transcriptase-loop-mediated isothermal amplification (RT-LAMP) assay was set up for rapid and efficient detection of BVDV. For this purpose, four primers were designed to recognize six distinct...

Real-time air quality forecasting (RT-AQF), a new discipline of the atmospheric sciences, represents one of the most far-reaching development and practical applications of science and engineering, poses unprecedented scientific, technical, and computational challenges, and generates significant opportunities for science dissemination and community participations. This two-part review provides a...

This paper presents an improvement of the Bandwidth Inheritance Protocol (BWI), the natural extension of the well-known Priority Inheritance Protocol (PIP) to resource reservation schedulers. The modified protocol allows for a better management of nested critical section, removes unneeded overheads in the management of task block and unblock events, and introduces a run-time deadlock detection ...