Infection by Epstein-Barr virus (EBV) generates several types of latency with different profiles of gene expression but with expression of Epstein-Barr nuclear antigen 1 (EBNA-1) in common. The BamHI Q promoter (Qp) is used for the transcription of EBNA-1 mRNA in type I latency, which is an EBV infection state exemplified by Burkitt's lymphoma (BL). However, Qp is inactive in type III latency, ...

We show that all but 4489 integers n with 4 < n ≤ 4 ·1030 cannot occur as the order of a circulant Hadamard matrix. Our algorithm allows us to search 10000 times farther than prior efforts, while substantially reducing memory requirements. The principal improvement over prior methods involves the incorporation of a separate search for double Wieferich prime pairs {p, q}, which have the property...

Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA-1) is the essential protein for maintenance of the EBV episome and establishment of latency. The BamHI Q promoter (Qp) is used for the transcription of EBNA-1 mRNA in type I and type II latency, which are EBV infection states exemplified by Burkitt's lymphoma and nasopharyngeal carcinoma. However, Qp is inactive in type III latency, and other pro...

In the context of global urbanization, urban flood risk in many cities has become a serious environmental issue, threatening the health of residents and the environment. A number of hydrological studies have linked urban flooding issues closely to the spectrum of spatial patterns of urbanization, but relatively little attention has been given to small-scale catchments within the realm of urban ...

We present a frequency-independent three-dimensional (3-D) compressional wave attenuation model (indicated by the reciprocal of quality factor Qp) for Kı̄lauea Volcano in Hawai‘i. We apply the simul2000 tomographic algorithm to the attenuation operator t∗ values for the inversion of Qp perturbations through a recent 3-D seismic velocity model and earthquake location catalog. The t∗ values are me...

Given a non-negative integer k, we construct a lattice 3-simplex P with the following property: The affine semigroup QP associated to P is not normal, and every element q ∈ QP \ QP has lattice distance at least k above every facet of QP .