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lead to the activation of OMA1 protease activity towards OPA1? Given previous work from the Langer lab, one model to potentially explain the results of Ehses et al. [6] would invoke the involvement of inner membrane lipid microdomains [14]. Prohibitins are inner membrane proteins thought to possess chaperone-like activity. These proteins are found in very large, megadalton complexes thought to ...
late B cells, IL-4 has been found to activate cytotoxic T cells, modulate macrophage function, and cause B-cell immunoglobulin class switching.1,2 Our results and the I nterleukin 4 (IL-4) is primarily a T-lymphocyte and mast cell–derived cytokine with a variety of biologic functions. Originally described for its ability to stimuObjective: The interleukin 4 receptor has been demonstrated on the...
Jitka A. I. Virag,* Ethan J. Anderson,* Susan D. Kent, Harrison D. Blanton, Tracy L. Johnson, Fatiha Moukdar, Jonathan H. DeAntonio, Kathleen Thayne, Jian M. Ding, and Robert M. Lust Department of Physiology, Brody School of Medicine, East Carolina University, Greenville, North Carolina; and Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenvill...
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