antimicrobial activity of the polar and nonpolar extracts of the roots and aerial parts of peucedanum ruthenicum m. bieb., johreniopsis seseloides (c. a. mey.) pimenov and cervaria cervariifolia (c. a. mey.) pimenov were examined against gram-positive and gram-negative bacteria. the polar extracts of the roots and aerial parts displayed no activity against bacteria, while the nonoplar extracts ...

abstractpyrimidine nucleosides are constituents of fundamental structure of the cells. there has been considerable attentions in the chemistry of pyrimidine derivatives due to having a wide range of biological activities such as antiviral, anti-malarial agents, cytostatic, antithelemintic, antibacterial, adenosine receptor ligands, anti-cancer agents, compounds targeting delayed-type hypersensi...

objective: punica granatum, commonly known as pomegranate, has emerged as a medicinal plant with potential antimicrobial activity. the present study was planned to evaluate this activity against both gram positive staphylococcus aureus (s. aureus) and negative pseudomonas aeruginosa (p. aeruginosa) bacteria as well as against pathogenic yeast, candida albicans (c. albicans). material and method...

tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. it has broad spectrum activity, including staphylococcus aureus infections. this is the first study that evaluated the activity of tigecycline against staphylococcus aureus isolated from biological samples in iran. in vitro activity of tigecycline against 160 staphylococcus aureus including 99 methicil...

Tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. It has broad spectrum activity, including Staphylococcus aureus infections. This is the first study that evaluated the activity of Tigecycline against Staphylococcus aureus isolated from biological samples in Iran. In vitro activity of tigecycline against 160 Staphylococcus aureus including 99 methicil...

There has been special interest in the chemistry of quinolone and pyrimidine derivatives due to their diverse biological activities such as anticonvulsant, anti-malarial agents, antibacterial, antiviral, cytostatic, antithelemintic, antigenotoxic, anti-cancer agents. These compounds are also used as targeting delayed-type hypersensivity and anti-convulsant agents. As a part of our research work...

There has been special interest in the chemistry of quinolone and pyrimidine derivatives due to their diverse biological activities such as anticonvulsant, anti-malarial agents, antibacterial, antiviral, cytostatic, antithelemintic, antigenotoxic, anti-cancer agents. These compounds are also used as targeting delayed-type hypersensivity and anti-convulsant agents. As a part of our research work...

REP8839 is a selective inhibitor of methionyl-tRNA synthetase (MetRS) with antibacterial activity against a variety of gram-positive organisms. We determined REP8839 potency against Staphylococcus aureus MetRS and assessed its selectivity for bacterial versus human orthologs of MetRS. The inhibition constant (K(i)) of REP8839 was 10 pM for Staphylococcus aureus MetRS. Inhibition of MetRS by REP...

Indonesia has various beneficial plants species which has not been specifically cultivated yet. One of those plants was Blimbi (Averrhoa bilimbi L.). Blimbi had potential on Staphylococcus aureus and Escherichia coli bacteria as the antibacterial. Its nanoparticle became a carrier which dissolved, trapped, encapsulated, or attached the chemical preparation inside its matrix. This study aimed to...