To address the safety problems caused by clips being squeezed jacks and wire slipping in tensioning process of flat anchorages, we designed a limit plate to be used with anchorage, studied mechanical properties anchorage system after adding through numerical simulation. Lastly, was created applied practical engineering scenario test its performance. The results showed that newly changed butt po...

Cell anchorage is required for cell proliferation of untransformed cells, whereas anchorage-independent growth can be induced by oncogenes and is a hallmark of transformation. Whereas anchorage-dependent control of the progression of the G(1) phase of the cell cycle has been extensively studied, it is less clear whether and how anchorage may control other cell cycle phases and whether oncogenes...

INTRODUCTION The purpose of this study was to compare and measure the amount of anchorage loss with titanium microimplants and conventional molar anchorage during canine retraction. METHODS Subjects for this study comprised 10 orthodontic patients (7 women, 3 men) with a mean age of 19.6 years (range, 18 to 25 years), who had therapeutic extraction of all first premolars. After leveling and a...

Oncogenic K-Ras mutation occurs frequently in several types of cancers, including pancreatic and lung cancers. Tumors with K-Ras mutation are resistant to chemotherapeutic drugs as well as molecular targeting agents. Although numerous approaches are ongoing to find effective ways to treat these tumors, there are still no effective therapies for K-Ras mutant cancer patients. Here we report that ...

With the growing population and density in metropolitan areas, higher tendency to live in high-rise buildings, and increasing demand for parking lots, it seems necessary to excavate soil to construct underground spaces. During excavation work, as the height of the wall increases, special care should be taken to the wall stabilization to avoid any consequent damage including extensive property d...

Joan Eamer, Environment Canada, Whitehorse, Yukon, Canada; Etok Edwardsen, Fairbanks, Alaska; Carl Jack, Rural Alaska Community Action Program (RurAl CAP), Anchorage, Alaska; Suzanne Marcy, U.S. Environmental Protection Agency, Anchorage, Alaska; Angie Olrun, Aleutian/Pribilof Islands Association, Anchorage, Alaska; Michael Patkotak, Barrow, Alaska; Delbert Rexford, Barrow, Alaska; Alex Whiting...

Difluoromethylornithine (DFMO), a specific, irreversible, enzyme-activated inhibitor of ornithine decarboxylase activity, the first and rate-limiting step in polyamine biosynthesis, has been shown to inhibit neoplastic cell proliferation in culture. In most cases, such inhibition is not accompanied by cell loss, with the exception of multiple cell lines of human small cell lung carcinoma (SCC),...

The idea of absolute anchorage has always been an elusive goal for clinicians. Orthodontic mini-implants or temporary anchorage devices allow tooth movements previously thought to be impossible or difficult. Although extensive literature exists on use of temporary anchorage devices, their failures have been hardly focused upon, especially implant fracture. The following case report describes su...

with the growing population and density in metropolitan areas, higher tendency to live in high-rise buildings, and increasing demand for parking lots, it seems necessary to excavate soil to construct underground spaces. during excavation work, as the height of the wall increases, special care should be taken to the wall stabilization to avoid any consequent damage including extensive property d...