previous studies have suggested that ketamine, an n-methyl-d-aspartate (nmda) receptor antagonist, provides a pre-emptive analgesic effect and pre-emptive analgesia improves postoperative pain management. the aim of this study was to determine the effict of pre-incisional vs. post-incisional intravenous low dose of racemic ketamine in postoperative pain in children undergoing inguinal hernia re...

BACKGROUND There is controversy about the effectiveness of intraperitoneal local anaesthesia (LA) in laparoscopic surgery. The aim of the present randomized clinical trial was to compare the analgesic effect of pre-emptive (preoperative) versus postoperative intraperitoneal LA in two different types of laparoscopic surgery. METHODS Between July 2004 and January 2005, 133 consecutive patients ...

introduction: shorter hospital stay and less pain in comparison to open surgery considered to be major benefits for laparoscopic cholecystectomy. we compared the effect of intraperitoneal hydrocortisone plus bupivacaine with bupivacaine alone on pain relief following laparoscopic cholecystectomy.  methods: sixty two patients participated in this double-blind, randomized clinical trial. patients...

Purpose: Circumcision is one of the most common surgeries performed in the pediatric population. Multiple regional analgesic techniques, including caudal (CB) and penile block (PB), have championed as offering optimal analgesia for circumcision in the post-neonatal pediatric population without clear consensus. This meta-analysis sought to investigate CB and PB’s analgesic efficacy and the impac...

introduction: several mehods have been proposed to alleviate pain after hysterectomy. pre-emptive analgesia has been used to relieve pain following abdominal hysterectomy with conflicting results. this study was performed to evaluate the efficacy of pre-incision skin infiltration of lidocaine in relieving postoperative pain in patients undergoing abdominal hysterectomy.  methods: 60 patients wi...

The use of non-opioid analgesics following surgery has proven beneficial in managing pain and decreasing adverse outcomes surgery. Data assessing related to opioid is limited kidney transplant recipients (KTRs). We evaluated the effectiveness implementing a reduced no protocol KTRs. This retrospective cohort study included adult KTRs between January 2017 July 2019 with multimodal analgesic (MAP...