In our ongoing study to evaluate the antiprotozoal activity of alkamides from Asteraceae, a dichloromethane extract from the roots of Anacycluspyrethrum L. showed a moderate in vitro activity against the NF54 strain of Plasmodium falciparum and against Leishmaniadonovani (amastigotes, MHOM/ET/67/L82 strain). Seven pure alkamides and a mixture of two further alkamides were isolated by column chr...

Epilepsy is a brain disorder which affects about 50 million people worldwide. Ineffectiveness of the drugs in some cases and the serious side effects and chronic toxicity of the antiepileptic drugs lead to use of herbal medicine as a form of complementary and alternative medicine. In this review modern evidences for the efficacy of antiepileptic medicinal plants in Traditional Iranian Medicine ...

Medicinal plants constitute a potential source of bioactive molecules which can provide new antimicrobial agents. This study aims to evaluate the antibacterial activity against multidrug resistant bacteria associated with skin infections and screen phytochemical composition Thymelaea hirsuta Anacyclus pyrethrum from Algeria. For this purpose, four multi-drug were isolated pus samples compared S...

Activit, a herbomineral formulation, containing extracts derived from Mucuna pruriens, Withania somnifera, Argyreia speciosa, Centella asiatica, Tribulus terrestris, Asparagus racemosus, Piper longum, Anacyclus pyrethrum, Nux vomica, Tinospora cordifolia and Shring bhasma, was studied for its protective effect against gastric lesions induced by ethanol and pylorus-ligation. The formulation was ...

Objective. To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant N-alkylamide pellitorine. Methods. Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer, (2) the rat gut after oral administration, and (3) the BBB in mice after intravenous and intracer...