نتایج جستجو برای: amsterdam ii criteria
تعداد نتایج: 832174 فیلتر نتایج به سال:
Gladiolus is cultivated as a high-value ornamental plant in the worldwide and it has the highest cultivation area and the highest level of underground organs imports in Iran. In this study, in order to investigate indirect regeneration of Amsterdam and Advance Red cultivars an experiment was conducted in a completely randomized design with three replications. For callogenesis, bud sprout (apica...
PURPOSE Newfoundland has one of the highest rates of colorectal cancer in North America. The most common hereditary form of colorectal cancer is hereditary nonpolyposis colorectal cancer caused by mutations in genes involved in mismatch repair. Our purpose was to determine the proportion of hereditary colorectal cancer and to determine the genetic basis of disease in both population and clinica...
Family history is a strong predictor of colorectal cancer risk; however, a diagnosis of colorectal cancer among first-degree relatives has not been systematically investigated as a function of the colorectal cancer molecular subtypes related to tumor microsatellite instability (MSI) status. We investigated whether the observable familial colorectal cancer risks differed according to tumor MSI s...
CONTEXT Genetic testing for cancer predisposition is evolving from purely research applications to affecting clinical management. OBJECTIVE To determine how often genetic test results for hereditary nonpolyposis colorectal cancer (HNPCC) can be definitively interpreted and used to guide clinical management. DESIGN Case-series study conducted in 1996 to 1998 in which a complete sequence anal...
The results of screening individuals referred to the Family Cancer Clinic at St Mark's Hospital from 1986 are presented. Colonoscopy was performed in 644 asymptomatic individuals (from 436 families) with a family history of colorectal cancer. Sixty nine (15.8%) of the families fulfilled the Amsterdam criteria for the hereditary non-polyposis colorectal cancer syndromes (HNPCC). Seven cases of c...
Hereditary non-polyposis colorectal cancer (HNPCC) is a very important clinical entity in oncology. In order to identify HNPCC, the international diagnostic criteria named "Amsterdam criteria" have been used. In this report, we present a case of an HNPCC patient who met the revised Amsterdam criteria after the sequential history taking in which a novel germline mutation of hMSH2 gene was detect...
Introduction. The aim of the study is to evaluate the incidence and phenotype genotype characteristics of hereditary colorectal cancer syndromes in Latvia in order to develop the basis of clinical management for patients and their relatives affected by these syndromes. Material and methods. From 02/1999-09/2002 in several hospitals in Latvia cancer family histories were collected from 865 patie...
To provide continuous growth of Amsterdam Airport Schiphol (AAS), the department Stakeholder Strategy and Development (SSD) of Amsterdam Airport Schiphol (AAS) introduces Noise Abatement Measures to create quieter aircraft operations and hence to be able to fly more frequent within the current environmental law related to aircraft noise. However, SSD faces difficulties with the evaluation regar...
OBJECTIVE To determine to what extent individuals with various family histories of colorectal cancer (from one to three or more affected first degree relatives) benefit from colonoscopic surveillance. DESIGN Prospective, observational study of high risk families, followed up over 16 years. SETTING Tertiary referral family cancer clinic in London. PARTICIPANTS 1678 individuals from familie...
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