In present study possible ameliorative efficacy of aqueous extract of bark of Alstonia scholaris (ASE) in cultured human lymphocytes against Bleomycin-induced cytogenetic alterations has been reported. Cultures were treated either alone with Alstonia scholaris aqueous bark extract (50μg/ml) or in combination with radiomimetic drug Bleomycin (15μg/ml). Positive implications about radioprotective...

objective: the main objective of the current study was to observe the ameliorative effect of withania somnifera on arsenic-induced testicular toxicity by exploring the crucial parameters such as sperm counts, sperm motility, hormonal assay and lipid peroxidation including histopathology. materials and methods: in the present study, arsenic in the form of sodium arsenite was administered orally ...

This study investigated the toxicity of sodium fluoride on male reproductive hormones and ameliorative effects extract Phyllantus amarus adult albino rats. The consisted six equal groups five rats that were administered with over a period two weeks. result indicates possible hormone lipid profile probable capacity to ameliorate this toxicity.

background: organophosphorus pesticides has been widely used in agriculture fields to control various crop insects and their extensive use pose human life at threat because of their adverse effects on human health. in this study, we checked the effects of gst polymorphism on ameliorative effect of curcumin and carvacrol against dna damages. methods: comet assay was used to assess the dna damage...

background: the main aim of the present study was to evaluate the ameliorative effect of curcumin on aflatoxin-induced changes in caput and cauda epididymis of mice. materials and methods: aflatoxin was obtained by growing aspergillus parasiticus in sucrose - magnesium sulphate - potassium nitrate - yeast extract (smky) liquid medium. pure curcumin (97% purity) was purchased from hi-media labor...

INTRODUCTION Multiple factors of vulnerability may lead to development of abnormal social behaviour and to important psychiatric diseases. The psychopathological characteristics present at individual level can lead to a pattern of population groups that are subject to developing mental illness risks. MATERIAL AND METHODS Multidisciplinary study (2009-2011) to assessing the current situation o...

Cadmium can cause oxidative damage in organisms through overproduction of free radicals and suppression the antioxidant defense system. Resveratrol is known as a nutraceutical with properties accepted to have protective effects toxicity heavy metals. In this study, we investigated if resveratrol could overwhelm toxic effect sub-acute cadmium exposure. Animals were divided following groups: 1) C...

Little is known about the neurobiological effects of psychotropic medications used in the treatment of children and adolescents diagnosed with a psychiatric disorder. This review provides a synopsis of the literature demonstrating the neural effects associated with exposure to psychotropic medication in youth using multimodal neuroimaging. The article concludes by illustrating how, taken togeth...