N -nitroso compounds, such as N -nitrosodiethylamine (NDEA), can be formed by the reaction of secundary amines with nitrosating agents, and are suspected to be involved in tumors in humans. NDEA has been considered a weak carcinogen in genotoxic assays probably due to the inefficient nitrosamine activation system that is used and/or to the efficient repair system. In this work, we evaluated the...

in the present study we aimed to evaluate the effects of methanolic extracts of the bulbs of garlic (allium sativum l., alliaceae) and persian shallot (allium ascalonicum l., alliaceae ) and leaves of sage (salvia officinalis l., lamiaceae ), ase, aae and soe respectively, on the antioxidant enzymes such as superoxide dismutase (sod), glutathione peroxidase (gpx) and catalase (cat) activities an...

Allium cepa L. is known to possess numerous pharmacological properties. Our aim was to examine the in vitro effects of Allium cepa L. extract (AcE) on Porphyromonas gingivalis LPS and Escherichia coli LPS-stimulated osteoclast precursor cells to determine cell viability to other future cell-based assays. Osteoclast precursor cells (RAW 264.7) were stimulated by Pg LPS (1 μg/mL) and E. coli LPS ...

AIMS The current study was designed to document medicinal plant species that are traditionally used to treat tuberculosis (TB) by Ghanaian communities. METHODS The medicinal plants used against TB or its signs and symptoms were selected using library and online published data searches. A guided questionnaire interview was also conducted with a botanist involved in plant collection at the Cent...

Allium ekimianum is described here as a new species. This taxon belongs to the genus Allium section Allium and grows in Elazığ Province (East Anatolia, Turkey). It is a narrowly distributed species and morphologically most similar to Allium asperiflorum and Allium sintenisii, and Allium erzincanicum but it is clearly differentiated due to the curved stem, smooth pedicel surfaces, bracteole arra...

Allium sativum L. belongs to a member of the onion family (Alliaceae) and has been used for both culinary and medical purpose. We cloned 4-coumarate:CoA ligase (4CL) from Allium sativum. 4-Coumarate:CoA ligase has an important role in the biosynthesis of plant secondary metabolites at the divergence point from general phenylpropanoid metabolism to several major branch pathways. Its deduced amin...

the medicinal plants have been used since ancient times and are still utilized by the majority of the population. hence, it is essential to investigate the cytotoxic and genotoxic effects of these plants. the aim of this study was to evaluate the toxic effects of fennel seeds decoctions, traditionally used in iran as an herbal remedy.  the cytotoxicity was tested in vitro using allium cepa l. r...