PURPOSE To report the case of a patient with bilateral frosted branch angiitis and undiagnosed Hodgkin lymphoma. METHODS Review of clinical history, laboratory findings, histology of supraclavicular lymph node biopsy, and follow-up. RESULTS A 22-year-old man presented with a sudden, bilateral visual loss. Fundus examination and fluorescein angiography disclosed a bilateral frosted branch an...

Primary angiitis of the central nervous system is a rare idiopathic vasculitis affecting small- and medium-sized vessels, isolated to the brain, leptomeninges and spinal cord. We report a case of biopsy-proven primary angiitis of the central nervous system, displaying some atypical features. This case highlights several key diagnostic and management issues of the disorder as well as its potenti...

Isolated angiitis of the central nervous system (CNS) is a rare condition with an incidence estimated at less than 1:2 000 000 (Moore, 1999). It was defined, in 1959, as an idiopathic vasculitis restricted to small leptomeningeal and parenchymal arteries and veins, without apparent systemic involvement (Cravioto and Feigin, 1959). Almost 50 years later, the affliction remains poorly recognized,...

CHURG-STRAUSS SYNDROME Churg-Strauss syndrome is a rare small vessel vasculitis manifested by fever, asthma, and hypereosinophilia. This disease is also referred to as allergic angiitis and granulomatosis, • A patient’s combined genetic predisposition and regulatory mechanisms control expression of the immune response to antigens. • Negative test results for antineutrophil cytoplasmic antibodie...

Churg-Strauss syndrome is a small and medium vessel vasculitis that is also known as allergic granulomatous angiitis. It most commonly presents with an asthma like symptoms. It was first described in Mount Siani Hospital, New York in 1951 by Jacob Churg and Lotte Stauss and was recognised after the study of a series of 13 patients who had asthma, eosinophilia, granulomatous inflammation necroti...

INTRODUCTION Frosted branch angiitis usually occurs in children and presents with severe sheathing of all retinal vessels mimicking the appearance of frosted branches of a tree. OBJECTIVE To report a case of frosted branch angiitis in a pregnant lady. CASE We, hereby, report a case of a 24-year-old pregnant female who presented to us with the complaints of sudden diminution of vision in the...

In this case of biopsy-proved granulomatous angiitis, MR showed prominent leptomeningeal enhancement with comparatively little parenchymal involvement. Pathologically, granulomatous angiitis chiefly affects small vessels, with a predilection for those in the leptomeninges. Although marked leptomeningeal enhancement is not the most common finding, vasculitis should be added to the differential d...

We report the case of a 32-year-old woman with isolated angiitis of the central nervous system. This case shows that high levels of pleocytosis may not rule out isolated angiitis of the central nervous system if this diagnosis can be considered on clinical grounds.

Churg-Strauss syndrome (CSS), also known as allergic granulomatous angiitis, is a systemic necrotizing vasculitis of the small and medium vessels. It typically occurs in conjunction with a history of asthma, eosinophilia, pulmonary infiltrates, and vasculitis, but cases without asthma have also been reported (1-2). CSS has rarely been reported in pediatric patients. Here, we report a nine-year-...