background: the t allele of the hepatic lipase (hl) c-514t polymorphism was previously found to be associated with lower plasma hl activity. here, we examined the association between this polymorphism and plasma hdl-cholesterol concentrations in patients with coronary arteries stenosis. methods: we studied 342 subjects undergoing coronary angiography in two groups of non cad (n=146) and cad (n=...

scid is a lethal genetic autosomal recessive disorder that has been observed in humans, dogs, mice, and horses. affected animals are incapable of generating specific antigens for immune responses needed to protect them from infectious diseases. the frequency of affected recessive allele varies in different regions so that the outcome of normal breeding with carriers of recessive alleles is diff...

the aim of this research was to study two alleles bf2*13, bf2*21 of bf2 gene in class i mhc in two population at sistan and baluchestan province. mhc is a gene cluster that play regulation role in immune system. many experiments showed association between the gene cluster and resistance and sensitiveness against different diseases and, also productivity traits. bf2 gene is among associated loci...

tumor necrosis factor alpha-inducible protein 3 (tnfaip3) gene polymorphisms have been reported to be associated with the susceptibility to several immune-related diseases. here we investigated the effect of tnfaip3 gene polymorphisms on the risk of allergic rhinitis (ar) in a chinese han population. the case-control study included 540 ar patients and 524 healthy controls. genotyping for tnfaip...

Objective(s): Mutations in the UGT1A1 gene are responsible for hyperbilirubinemia syndromes including Crigler-Najjar type 1 and 2 and Gilbert syndrome. In view of the genetic heterogeneity and involvement of large numbers of the disease causing mutations, the application of polymorphic markers in the UGTA1 gene could be useful in molecular diagnosis of the disease. Materials and Methods: In the...