in this study 110 samples of amniotic fluid of sheep at different stage of pregnancy were assessed for creatinine (cr), alkaline phosphatase (alp), aspartate aminotransferase (ast), creatin kinase (ck), lactate dehydrogenase (ldh) and arginase. significant increase (p

OBJECTIVE To investigate the influence of a three-dimensional cell culture model on the expression of osteoblastic phenotype in human periodontal ligament fibroblast (hPDLF) cultures. MATERIAL AND METHODS hPDLF were seeded on bi-dimensional (2D) and three-dimensional (3D) collagen type I (experimental groups) and and on a plastic coverslip (control) for up to 14 days. Cell viability and alkal...

Alkaline phosphatase (ALP; EC 3.1.3.1) isoenzymes were measured in the plasma of 63 untreated hyperthyroid patients (the hyperthyroid group), 58 treated hyperthyroid patients, and 100 blood donors. Total, liver, and bone ALP activities were significantly higher in the hyperthyroid group than in the treated hyperthyroid group or the blood donors. Bone ALP was more frequently and more markedly ab...

background: collagen, the most abundant protein in the human body, and as an extracellular matrix protein, has an important role in the fiber formation. this feature of the collagen renders  establishment of the structural skeleton in tissues. regarding specific features associated with the collagen, such as, formation of the porous structure, permeability and hydrophilicity, it can also be use...

Background: COPD (Chronic Obstructive Pulmonary Disease) is defined as a disease state characterized by airflow limitation that is not fully reversible. The airflow limitation is usually both progressive and associated with an abnormal inflammatory response of the lungs to noxious particles and gases. Tobacco smoke remains the main etiological agent. COPD inflammation initiated by tobacco smoke...

Diagnosis Serum alkaline phosphatase (ALP) measurement: Measurement of serum ALP activity has been used as a screening test for HAC. However, the best way to use measurement of ALP activity may be as a means to rule out the diagnosis of HAC. The sensitivity of this laboratory test is high, as ALP is above normal in 90% of dogs with HAC. 2 However, the specificity is very low. Scottish terriers ...

conclusions the elevation of hmw-alp activity in cu treated animal suggests the occurrence of biliary disease. this may be used as a biomarker for the diagnosis of copper toxicity. results obtained data showed that with increasing administration of copper, the alp activity was elevated significantly. in comparison with the control group the elevations were between 20%-56% using gel filtration c...

The aim of this work was to assess the relationship of both total alkaline phosphatase (ALP) and bone-specific alkaline phosphatase (BsALP) with the course and outcome of operatively treated long-bone fractures. The activity of total ALP and BsALP was measured in 41 patients with a long bone fracture, comprising 26 men and 15 women. All patients were treated operatively. Total ALP and BsALP lev...

In this present study, we fabricated an LSI-based amperometric chip device with highly temporal and spacial resolution for electrochemical imaging, applied to detection of alkaline phosphatase (ALP) activity and respiration activity of embryonic stem (ES) cells.