Epigalloccatechin-3-gallate (EGCG) is the main polyphenol component of green tea (leaves of Camellia sinensis). EGCG is known for its antioxidant, anti-inflammatory, antiviral, and anti-carcinogenic properties. Here, we identify EGCG as a new inhibitor of ocular angiogenesis and its vascular permeability. Matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) play a key ...

Purpose Corneal neovascularization and scarring commonly lead to significant vision loss. This study was designed to determine whether a small-molecule inhibitor of galectin-3 can inhibit both corneal angiogenesis and fibrosis in experimental mouse models. Methods Animal models of silver nitrate cautery and alkaline burn were used to induce mouse corneal angiogenesis and fibrosis, respectivel...

background : burn wounds are one of the health problems in modern societies that are associated with irreparable harms and many side problems for patients and their families. infection due to burn wounds is the main cause of death in such patients. one of the methods to prevent infection of burn wounds is topical antibiotic ointments. this study aimed to investigate and identify effective ointm...

PURPOSE Endostatin plays an important role in inhibiting corneal neovascularization (CNV). The aim of this study was to evaluate the antiangiogenic activities of lipid-mediated subconjunctival injection of the modified RGDRGD (arginine- glycin- aspartic- arginine- glycin- aspartic- endostatin gene in a rabbit model of neovascularization in vivo. METHODS A modified human endostatin gene contai...

background self-inflicted burn injuries carry considerable mortality and morbidity among otherwise fit young individuals. this study assessed the epidemiologic pattern and outcome of these injuries in a burn care facility in pakistan. methods the study was carried out at pakistan institute of medical sciences (pims) burn care centre in islamabad over a period of 2 years. it included all adult p...

background: general practitioners are the first who visit burn patients and they first calculate burn size and required fluid for the patient. error in calculation can be disastrous. the purpose of this study is to compare four methods of estimating burn size to teach students. methods: this is a descriptive-analytic study on 37 medical students. four methods of estimating burn percentage was t...

Kenaf fiber has been studied for biocomposites reinforcement due to its renewable and carbon neutrality. Meanwhile, polypropylene sheets are easily processed considered a prospective thermoplastic matrix source biocomposites. Hence, the combination of both materials is expected form an attractive biocomposite. This study aimed optimize permanganate treatment on tensile properties water absorpti...

Organ dysfunction and failure are important for burned patients as they increase morbidity and mortality. Recent evidence has suggested that organ injuries are occurring earlier after burns, and are more common than previously thought. In this study we have assessed the extent to which liver function, assessed by the plasma disappearance rate of indocyanine green (PDR(ICG)), is affected in pati...

normal 0 false false false en-us x-none fa microsoftinternetexplorer4 objective: occupational burns are among the important causes of work-related fatalities and absenteeism. epidemiologic assessment of these injuries is important to define high-risk jobs. we designed this study to evaluate the epidemiology of occupational burns in yazd, an industrial province in iran. materials and methods: th...