conclusions the elevation of hmw-alp activity in cu treated animal suggests the occurrence of biliary disease. this may be used as a biomarker for the diagnosis of copper toxicity. results obtained data showed that with increasing administration of copper, the alp activity was elevated significantly. in comparison with the control group the elevations were between 20%-56% using gel filtration c...

background: to investigate the effect of cana2-edta and experimental diabetes (iddm) on zinc and carbohydrate metabolism and the activities of got, gpt and alkaline phosphatase. methods: forty male normal albino (wistar) rats of 8 weeks of age were fed with a basal diet. twenty rats were then intraperitoneally injected with alloxan to induce diabetes. then after one week ten rats from each grou...

introduction: salivary calcium and phosphate levels might have a relationship with dental caries severity. evaluation of different indexes such as alkaline phosphatase, which increases salivary phosphate levels, and hydroxyapatite ion activity, which reflects salivary calcium and phosphate levels, might help determine the risk of dental caries. the aim of the present study was to compare saliva...

protein tyrosine phosphatases (ptpases) regulate tyrosine phosphorylation of target proteins involved in several aspects of cellular functions. enzyme activities of the ptpases in cytosolic and particulate fractions of rat ascites hepatoma cell lines were determined and compared with those of normal rat liver. our present data revealed that although there was no neoplatic-specific alteration of...

human brucellosis is a major health problem in developing countries. a number of patients with human brucellosis do not recover from the acute stage of the disease and pass into the chronic form. since the pathophysiology of this change is not well understood, we studied the t-cell subsets during the acute, subacute and chronic forms of human brucellosis. in this study we found alterations in t...

Günümüzde alkol alımı sindirim sistemi hastalıkları başta olmak üzere birçok hastalığın önemli bir etkenidir. Dopamin agonistlerinin kaynaklı hasarlar üzerinde iyileşmeye yardımcı olduğunun bilinmesine karşın, bupropionun etanol değişen biyokimyasal parametreler üzerindeki etkileri tam olarak açıklığa kavuşturulmamıştır. Bu çalışma uygulaması ile bazı etkisini değerlendirmek için gerçekleştiril...

background: recently, embryonic stem (es) cells have become very important resources in basic medical researches. these cells can differetiate into derivatives of all primary germ layers. objectives: in order to isolate embryonic stem cells in vitro, the blastocyst were cultured and the morphological aspects, population doubling time, alkalin phosphatse and differentiation properties of the cel...