The purpose of the current work was to study the role of Dunaliella salina extract in ameliorating Alzheimer ́s disease (AD) in rat brain. Aluminium chloride (AlCl3) was orally administered to male albino rats (100mg/kg/day for six weeks), while, D. salina ethanolic extract (150mg/kg/day for six weeks) was orally administered post AlCl3 treatment. At the end of experiment, AlCl3 treatment marked...

A new kind of ionic liquid based on the complexation of dipropyl sulfide (DPS) and AlCl3 has been prepared. The equivalent concentration of AlCl3 in the ionic liquid is as high as 2.3 M. More importantly, it is highly fluidic and exhibits an ambient ionic conductivity of 1.25 × 10(-4) S cm(-1). This new ionic liquid can be successfully used as an electrolyte for electrodeposition of aluminum.

The aim of the present study was to investigate toxic effects aluminum chloride (AlCl3) on reproductive organs, as well as, protective effect propolis against AlCl3-induced toxicity in male rats. Eighty adult fertile Sprague Dawley albino rats were randomly divided into four groups 20 each. Group 1: served control group and received only distilled water. 2: a daily ingestion 80 mg/kg AlCl3. 3: ...

The effect of Lewis acid on the structure and H2 productivity of a diiron dithiolate complex was investigated by using density functional theory (DFT) calculations. When a model molecule of [(CH3SH)(CO)2Fe(p)(mu-SCH2NHCH2S)Fe(d)(CO)3] was geometrically optimized, two isomers were found: one is the unrotated structure (1) with no ligand between two Fe atoms and the other is the rotated structure...

Cyclooxygenase (COX) enzymes are expressed in the brain; however, their role in hippocampus-dependent and cortex-dependent cognitive functions remains to be fully elucidated. The aim of the present study was to comparatively investigate the effects of piroxicam, a selective COX-I inhibitor, and celecoxib, a selective COX‑II inhibitor, on cognitive functions in an AlCl3‑induced neurotoxicity mou...

BACKGROUND Having considered how bioavailable aluminium (Al) may affect ecological systems and animals living there, especially cattle, and in search for a preventive dietary treatment against Al toxicity, we aimed to test the protective role of fenugreek seeds against chronic liver injury induced by aluminum chloride (AlCl3) in Wistar rats. RESULTS Five months of AlCl3 oral exposure (500 mg/...

The effects of chronic AlCl3 exposure on spatial memory in rats remain controversial. Since some toxic metals such as aluminum when entered the body, can contribute to diseases such as Alzheimer, in this study the time course effect of the systematically administered AlCl3 on the spatial memory retention in the Morris Water Maze was investigated. Rats were treated with AlCl3 (1 gr/lit) for two,...

Aluminum (Al) is present in the daily life of humans, and the incidence of Al contamination increased in recent years. Long-term excessive Al intake induces neuroinflammation and cognition impairment. Neuroinflammation alter density of dendritic spine, which, in turn, influence cognition function. However, it is unknown whether increased neuroinflammation is associated with altered density of d...