BACKGROUND Cancer chemotherapy is still hampered by clinical failures due to multi-drug resistance (MDR) of tumor cells. In the present study, we have investigated the cytotoxicity of 20 methanol extracts from 10 medicinal plants against the sensitive leukemia CCRF-CEM cells. The most cytotoxic extracts were then further tested on a panel of 8 human cancer cell lines, including various MDR phen...

Albizia lebbeck (AL) commonly known as shirish, has number of therapeutic properties. AL is an economically important plant for industrial and medicinal uses. The leaves are good fodder with much protein content.The plant contains saponin, macrocyclic alkaloids, phenolic glycosides and flavonols.In Ayurvedic medicine, it is considered as an antidote against all type of poisons. Many ayurvedic f...

In order to continue the research of natural compounds of interest such as pesticides and therapeutic molecules in endemic species of Albizia from Madagascar, potentials of Albizia odorata seed extract were assessed. A toxic saponin (saponoside), named Albodorine, was isolated by extraction with hot ethanol or distilled water followed by purification procedure comprising n-butanol partition, pr...

Objective: To evaluate the alpha amylase inhibitory activity of different extract of bark of Albizia lebbeck (L.) Benth. Methods: Bark of A. lebbeck was collected and air dried. Extraction of flavonoid, alkaloid and steroid carried out using standard methods. Extracts in different polar and non polar solvents were extracted using soxhlet method. Filtered extracts were subsequently tested for al...

Bioassay-guided fractionation of a CH(2)Cl(2)-MeOH extract of the aerial parts of Albizia inundata resulted in the isolation of two new natural oleanane-type triterpene saponins {3-O-[α-L-arabinopyranosyl(1→6)]-2-acetamido-2-deoxy-β-D-glucopyranosyl oleanolic acid (1) and 3-O-[α-L-arabinopyranosyl(1→2)-α-L-arabinopyranosyl(1→6)]-2-acetamido-2-deoxy-β-D-glucopyranosyl acacic acid lactone (2)} al...

A new species, Bruchidius paicus (Insecta, Coleoptera) reared from the seeds of a leguminous tree, Albizia lebbeck (Fabaceae: Mimosoideae: Ingeae), is described from Northern Thailand. Inspection of genital and external morphological traits of B. paicus revealed that the new species belongs to Bruchidius Group 5 (sensu ). The definition of Group 5 is reviewed based on both external and genital ...

Trypanocidal and cytotoxic effects of traditionally used medicinal plants of Ethiopia were evaluated. A total of 60 crude plant extracts were prepared from 30 plant species using CH2Cl2 and MeOH. Effect upon cell proliferation by the extracts, for both bloodstream forms of Trypanosoma brucei brucei and human leukaemia HL-60 cells, was assessed using resazurin as vital stain. Of all CH2Cl2 and M...

The alcoholic and aqueous extracts of five medicinal plants (Cassia fistula, Albizia lebbeck, Cassia occidentalis , Sphaeranthus indicus and Vitex nigundo) collected from Uttarakhand, North India; were evaluated for antibacterial activity by Agar diffusion method against medically important bacteria viz. B. subtilis, K. pneumonia, E. coli, Enterobacter aerogenes, Pseudomonas aeruginosa, S. aure...