نتایج جستجو برای: akinesia

تعداد نتایج: 770  

Journal: :Journal of Clinical Movement Disorders 2017

Journal: :Neuroreport 2006
Ned Jenkinson Dipankar Nandi Rebecca Oram John F Stein Tipu Z Aziz

The symptom of Parkinson's disease that is most disabling and difficult to treat is akinesia. We have previously shown that low-frequency stimulation of the pedunculopontine nucleus can alleviate such akinesia in a macaque rendered Parkinsonian using 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine. Here, we have extended that study to show that adding stimulation of the pedunculopontine nucleus to...

2016
Hakimeh Sadeghian Aliasghar Kousari Shahla Majidi Mehrnaz Rezvanfard Ali Kazemisaeid Seyed Ali Moezzi Ali Vasheghani Farahani Morteza Abdar Esfahani Mohammad Sahebjam Arezoo Zoroufian Afsaneh Sadeghian

Background: It is not clear whether the latest activation sites in the left ventricle (LV) are matched with infracted regions in patients with ischemic cardiomyopathy (ICM). We aimed to investigate whether the latest activation sites in the LV are in agreement with the region of akinesia in patients with ICM. Methods: Data were analyzed in 106 patients (age = 60.5 ± 12.1 y, male = 88.7%) with I...

2007
Abdul Kader M Mahfouz Hassan M Al Katheri

PURPOSE Evaluate efficacy of superficial peribulbar anesthesia for cataract extraction compared with conventional peribulbar anesthesia. SETTING Department of Ophthalmology, Al Nahdha Hospital (Tertiary Ophthalmic and ENT Hospital) and Magraby Eye & Ear Center, Muscat, Sultanate of Oman. METHODS Patients scheduled for cataract extraction with intraocular lens implantation were randomly divi...

Journal: :Journal of Neural Transplantation & Plasticity 1992
T. Schallert D. Norton T. A. Jones

In transplantation research on Parkinson's disease, behavioral evidence of graft-specific improved function is as necessary as anatomical or chemical data in evaluating the success of the procedure. The circling model of Ungerstedt has been widely adopted to provide such evidence, in part because it is so convenient and (relative to primate models) inexpensive. In this model 6-hydroxydopamine (...

Journal: :European Heart Journal 2022

Abstract Background/Purpose Takotsubo syndrome (TS) is an acute form of heart failure with similar mortality and clinical presentation as myocardial infarction. The pathophysiology the potentially life-threatening only partially understood. This experimental study aimed to produce a human-like TS model high reproducibility low mortality. Rats have been small-animal choice for preclinical studie...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1995
M Olsson G Nikkhah C Bentlage A Björklund

Methods for the assessment of akinesia in the unilateral rat Parkinson model have so far been lacking. The experiments reported here evaluate the usefulness of a new "stepping test" to monitor forelimb akinesia in rats with unilateral 6-hydroxydopamine (6-OHDA) lesions of the mesencephalic dopamine (DA) system, and to assess the ability of DA-receptor agonists and fetal DA neuron transplants to...

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