In the presence of oxygen aqueous solutions of the binuclear complex [cobalamin-^-NCFe(CN)5]3' undergo a redox photolysis (0 ~ 2 x 10'3 at Airr = 405 nm) which yields aquocobalamin and [Fe(CN)6]3\ It is suggested that this photoreaction is induced by direct metal-tometal charge transfer (MMCT) excitation. On the contrary, [cobalamin-fx-NC-Ru(CN)5]3' is photo-inert because a reactive MMCT state ...

BACKGROUND polypharmacy is an important risk factor for falls, but recent studies suggest only when including medications associated with increasing the risk of falls. DESIGN a prospective, population-based cohort study. SUBJECTS 6,666 adults aged ≥50 years from The Irish Longitudinal study on Ageing. METHODS participants reported regular medication use at baseline. Any subsequent falls, ...

RESEARCH DESIGN AND METHODSdWe undertook a cohort study using linked administrative healthcare and laboratory databases in Alberta, Canada. From 1 January 2004 to 31March 2009, we included all outpatients 66 years of age and older who had at least one serum creatinine and one A1Cmeasured. To examine the independent association between hospitalized hypoglycemia and all-cause mortality, we used t...

OBJECTIVE Use of preexposure prophylaxis (PrEP) for HIV raises concerns about sexually transmitted infection (STI) incidence because of decreased condom use among MSM. This study examines whether PrEP is associated with STIs in the 12 months following PrEP prescription relative to the 12 months prior to PrEP and if STI rates are higher among PrEP users relative to individuals receiving postexpo...

Motivation: During adaptive immune responses, activated B cells expand and undergo somatic hypermutation of their immunoglobulin (Ig) receptor, forming a clone of diversified cells that can be related back to a common ancestor. Identification of B cell clonotypes from high-throughput Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) data relies on computational analysis. Recently, we pr...

There is warranted interest in assessing the association between residential radon exposure and the risk of childhood cancer. We sought to evaluate the association between residential radon exposure and the incidence of childhood lymphoma in Texas. The Texas Cancer Registry (n = 2147) provided case information for the period 1995-2011. Denominator data were obtained from the United States Censu...

Background: The objectives of this study were to assess the role of HSV-2 status, first, on HIV acquisition by young men and secondly, on the protective effect of male circumcision on HIV acquisition. Methods: We used data collected during a male circumcision trial conducted in Orange Farm (South Africa). We estimated adjusted incidence rate ratios (aIRR) using survival analysis and background ...

Generally, severity, any additional damage to the joint surface, and optimal rehabilitation influence recovery of an ankle injury. Optimal is only approach for a human heal as soon possible. Ankle injury robots (AIRRs) are designed fulfil ideal by providing required accuracy, consistency, repeatability, compared conventional methods. This review explore performance existing AIRR using SWOT anal...

To date, genes identified and transcriptionally regulated by the AirSR TCS have been involved in energy production and cellular homeostasis of the staphylococcal cell. It is well accepted that the state of cellular metabolism impacts the expression of virulence factors in Staphylococcus aureus. For this reason, we conducted experiments to determine if the AirSR TCS contributes to the pathogenes...