Cystic fibrosis (CF) is a chronic progressive pulmonary disorder caused by mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene. A CF lung is generally characterized by obstructed airflow to an extent that leads to destruction of airway wall support structure. Airway resistance, resulting from both laminar and turbulent flow, is an important mechanical factor contrib...

Various bedding materials used in infancy, including duvets (or continental quilts), were tested for airflow using the British Standards Institution tests for pillows or fabrics. Resistance was also measured when the items were placed on a dummy infant face. Measurements were made on washed and unwashed garments, which were tested both dry and wet. Results suggest that all the bedding materials...

Rhinoplasty is one of the most common and challenging cosmetic procedures. One of the complications of rhinoplasty associated with dissatisfaction is nasal obstruction, which is often due to narrowing of the nasal valve area. Application of certain procedures such as turbinoplasty can prevent and correct this problem. This study aim was to investigate the effect of inferior turbinoplasty in red...

OBJECTIVE To evaluate whether virtual surgery performed on 3-dimensional (3D) nasal airway models can predict postsurgical, biophysical parameters obtained by computational fluid dynamics (CFD). METHODS Presurgery and postsurgery computed tomographic scans of a patient undergoing septoplasty and right inferior turbinate reduction (ITR) were used to generate 3D models of the nasal airway. Prio...

An index obtained from tidal expiration, the ratio of time to peak tidal expiratory flow (tPTEF) to expiratory time (tE), discriminates between groups with and without airflow obstruction in infants and children and correlates with other measurements of airflow obstruction in adults. The aim of this study was to determine whether the diagnosis of airflow obstruction could be made from an analys...

This issue includes an important paper by BARRY et al. [1] in which the changes in nasal peak inspiratory flow (NPIF), and oral peak inspiratory flow (OPIF), during acclimatized exposure to low barometric pressure (equivalent to a simulated altitude of 8000 m, about the height of Mount Everest) of subjects in a hypobaric chamber were analysed. The changes were presumably due to hypoxia and its ...

BACKGROUND in a previous study, we showed that the ability to detect a rise in airflow resistance at rest was reduced in some non-asthmatic subjects in old age. OBJECTIVE to determine whether airflow resistance detection is attenuated in elderly subjects with asthma. METHODS we studied 60 adult subjects with stable asthma (age range 20-88). Progressive external airflow resistance loading wa...

Background: The aim of this study was to compare the number of repetitions to volitional failure, the blood lactate concentration, and the perceived exertion to resistance training with and without an airflow-restricting mask. Methods: Eight participants participated in a randomized, counterbalanced, crossover study. Participants were assigned to an airflow-restricting mask group (MASK) or a co...

Computational Fluid Dynamics (CFD) is fast becoming a useful tool to aid clinicians in pre-surgical planning through the ability to provide information that could otherwise be extremely difficult if not impossible to obtain. However, in order to provide clinically relevant metrics, the accuracy of the computational method must be sufficiently high. There are many alternative methods employed in...