Report of a Case. A 37-year-old Nigerian man with a 14year history of bilateral Mooren ulceration had a right corneal perforation and a desmetocele in his severely damaged left eye (Figure, A and B). Snellen visual acuity was 6/60 OD, improving to 6/36 OD with pinhole, and hand movements OS. Systemic cyclosporine at a dosage of 5 mg/kg/d and prednisolone tapering from 1 mg/kg/d and ceasing afte...

Clinicians tend to underestimate potential modest benefits of chemotherapy. They are often reluctant to refer patients for chemotherapy, perhaps because they expect the side effects to outweigh any perceived benefits. However, patients are much more ready to accept chemotherapy, even when the likely benefits are small. Quality of life, change in performance status, and relief of tumor-related s...

In a series of fifteen aggressive mentally subnormal patients treated with lithium carbonate, there was an improvement in aggressive behaviour in eleven cases, three patients showed no change and one patient became worse during lithium treatment. The response to lithium therapy was assessed by clinical observation and retrospective analysis of daily ward reports. Treatment had to be discontinue...

Extra renal extra cranial malignant rhobdoid tumors (MRT) are rare, frequently lethal and affect mostly children. No definite treatment has been made and the role of radiation therapy is poorly defined. This report explains a 14 year old girl with MRT in her neck soft tissue. She is alive with no evidence of disease 18 months after diagnosis. Through the experience with this case, we suggested...

This is a report of a case with unilateral cavernous sinus thrombosis due to ipsilateral ethmoid sinusitis. A 10 year old female was admitted in our hospital with severe headache, purulent postnasal discharge, right eye proptosis and third cranial nerve palsy in the same eye. She had history of viral upper respiratory tract infection and then acute otitis media which did not improve with rou...

To the Editor: In a recent issue of the Journal, Soeda et al were able to show that rosuvastatin therapy reduced the lipid core and the size of lipid-rich-coronary plaques,1 adding to the known effect of statin therapy in stabilizing atherosclerotic plaques and reducing plaque vulnerability. When linking their findings regarding coronary plaques to those of a recent clinical trial on intracrani...